CAS 145307-34-2

(1R,3S)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-1H-2-benzopyran-5,6-diol hydrochloride (1:1)

Description:

The chemical substance known as (1R,3S)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-1H-2-benzopyran-5,6-diol hydrochloride (1:1) with CAS number 145307-34-2 is a complex organic compound characterized by its unique bicyclic and tricyclic structures. It features a benzopyran moiety, which is a fused ring system that contributes to its potential biological activity. The presence of an aminomethyl group indicates that it may exhibit properties related to amine functionality, possibly influencing its reactivity and interaction with biological targets. The hydrochloride salt form suggests enhanced solubility in aqueous environments, which is often advantageous for pharmacological applications. This compound may be of interest in medicinal chemistry, particularly in the development of therapeutic agents, due to its structural complexity and potential for diverse interactions within biological systems. Its stereochemistry, indicated by the (1R,3S) configuration, may also play a crucial role in determining its biological activity and specificity.

Formula: C₂₀H₂₈ClNO₃

InChI: InChI=1/C20H27NO3.ClH/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20;/h1-2,11-13,17-18,22-23H,3-10,21H2;1H/t11?,12?,13?,17-,18-,20?;/m0./s1

InChI key: InChIKey=BWHPNJVKFAPVOG-QYFJGNGUSA-N

SMILES: C(N)[C@@H]1O[C@H]([C@]23CC4(CC(C2)(CC(C3)(C4)[H])[H])[H])CC=5C1=CC=C(O)C5O.Cl

Synonyms:

• (-)-(1R,3S)-3-Adamantyl-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyran hydrate hydrochloride
• (1R)-1-(aminomethyl)-3-(tricyclo[3.3.1.1~3,7~]dec-1-yl)-3,4-dihydro-1H-isochromene-5,6-diol hydrochloride (1:1)
• (1R)-cis-1-Aminomethyl-3,4-dihydro-3-tricyclo[3.3.1.13.7]dec-1-yl-[1-h]-2-benzopyran-5,6-diolhydrochloride
• (1R,3S)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.1^3,7]dec-1-yl-1H-2-benzopyran-5,6-diol hydrochloride (1:1)
• (1R,3S)-1-(aminomethyl)-3-tricyclo[3.3.1.1~3,7~]dec-1-yl-3,4-dihydro-1H-isochromene-5,6-diol hydrochloride
• (1R-Cis)-1-(Aminomethyl)-3,4-Dihydro-3-Tricyclo[3.3.1.13,7]Dec-1-Yl-[1H]-2-Benzopyran-5,6-Diol Hydrochloride
• 1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.1^3,7]dec-1-yl-, hydrochloride (1:1), (1R,3S)-
• 1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.1^3,7]dec-1-yl-, hydrochloride, (1R-cis)-
• A 77636
• A 77636 Hydrochloride
• A-77636 hydrate hydrochloride
• 1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride, (1R-cis)-
• (1R,3S)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-1H-2-benzopyran-5,6-diol hydrochloride (1:1)
• 1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1), (1R,3S)-
• (-)-(1R,3S)-3-ADAMANTYL-1-(AMINOMETHYL)-3,4-DIHYDRO-5,6-DIHYDROXY-1H-2-BENZOPYRAN HYDROCHLORIDE
• A-77636 hydrochloride hydrate
• (?)-(1R,3S)-3-Adamantyl-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyran hydrochloride hydrate

A-77636 (hydrochloride)

CAS: 145307-34-2

Formula: C₂₀H₂₈ClNO₃

Purity: 95%

Molecular weight: 365.8942

Ref: IN-DA001KS5

A 77636 hydrochloride

CAS: 145307-34-2

A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).

Formula: C₂₀H₂₈ClNO₃

Purity: 99.57%

Color and Shape: Solid

Molecular weight: 365.89

Ref: TM-T21782

A 77636 hydrochloride

CAS: 145307-34-2

A 77636 hydrochloride

Purity: ≥98%

Molecular weight: 365.89g/mol

Ref: 54-BUP14273