CAS 1453222-26-8

SAH-EZH2

CAS: 1453222-26-8

EZH2/EPP inhibitor, Kd 320 nM. Reduces EZH2, H3K27me3; halts MLL-AF9 leukemia growth; drives monocyte-macrophage differentiation.

Formula: C₁₅₅H₂₅₆N₄₈O₄₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 3432.05

Ref: TM-TP2115

SAH-EZH2

CAS: 1453222-26-8

SAH-EZH2 is a small molecule that functions as a pharmacologic and natural compound. It is a lysine methyltransferase inhibitor, which blocks the methylation of histone proteins. SAH-EZH2 has been shown to be effective in vivo against autoimmune diseases and cancer. SAH-EZH2 also inhibits DNA replication and transcription, which may be due to its ability to suppress different genes via epigenetic regulation. SAH-EZH2 also binds to subunits of the DNA methyltransferases, preventing it from binding with other molecules. The result is that SAH-EZH2 disrupts the production of new proteins, leading to cell death by inhibiting protein synthesis.

Formula: C₁₅₅H₂₅₆N₄₈O₄₀

Purity: Min. 95%

Molecular weight: 3,432 g/mol

Ref: 3D-DIC22226