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Pioglitazone Hydrochloride

CAS 145350-09-0: Pioglitazone Hydrochloride

Description:Pioglitazone Hydrochloride is an antidiabetic medication primarily used to manage type 2 diabetes mellitus. It belongs to the thiazolidinedione class of drugs, which function as agonists of the peroxisome proliferator-activated receptor gamma (PPAR-γ). This action enhances insulin sensitivity in muscle and adipose tissue, thereby improving glucose uptake and utilization. The substance appears as a white to off-white crystalline powder, and it is soluble in water and methanol, which facilitates its formulation in various dosage forms. Pioglitazone Hydrochloride is typically administered orally and is often prescribed in conjunction with diet and exercise to achieve better glycemic control. Common side effects may include weight gain, edema, and an increased risk of heart failure, necessitating careful patient monitoring. Additionally, it has been associated with potential risks of bladder cancer, leading to specific recommendations regarding its use. Overall, Pioglitazone Hydrochloride plays a significant role in diabetes management, particularly for patients who are insulin-resistant.

Formula:C19H20N2O3S・HCl

InChI:InChI=1S/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H

  • Synonyms:
  • Pioglitazone HCl
  • 5-[[4-[2-(5-Ethyl-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione N-Oxide
  • Pioglitazone N-Oxide
  • 5-{4-[2-(5-Ethyl-1-Oxidopyridin-2-Yl)Ethoxy]Benzyl}-1,3-Thiazolidine-2,4-Dione
  • 5-[[4-2-(5-ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-thiazolidinedione Hydrochloride
  • [5-[[4-[2-(5-Ethyl-2-Pyridinyl)Ethoxy]Phenyl]Methyl]-2,4-] Thiazolidinedione Hydrochloride
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2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-1-oxido-2-pyridinyl)ethoxy]phenyl]methyl]-

CAS:145350-09-0

Ref: IN-DA001KTL

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Estimated delivery in United States, on Monday 24 Mar 2025
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Pioglitazone N-Oxide

CAS:145350-09-0

Ref: 4Z-P-107

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Estimated delivery in United States, on Tuesday 25 Mar 2025
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Pioglitazone N-Oxide

Controlled Product
CAS:145350-09-0

Ref: 86-MM0616.09-0025

25mg941.00 €
Estimated delivery in United States, on Thursday 27 Mar 2025
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Pioglitazone N-Oxide

Controlled Product
CAS:145350-09-0

Ref: TR-P471010

25mg1,516.00 €
2500µg205.00 €
Estimated delivery in United States, on Thursday 3 Apr 2025
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Pioglitazone N-oxide

CAS:145350-09-0

Ref: 3D-FP27056

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