CAS 145350-09-0: Pioglitazone Hydrochloride

Description:Pioglitazone Hydrochloride is an antidiabetic medication primarily used to manage type 2 diabetes mellitus. It belongs to the thiazolidinedione class of drugs, which function as agonists of the peroxisome proliferator-activated receptor gamma (PPAR-γ). This action enhances insulin sensitivity in muscle and adipose tissue, thereby improving glucose uptake and utilization. The substance appears as a white to off-white crystalline powder, and it is soluble in water and methanol, which facilitates its formulation in various dosage forms. Pioglitazone Hydrochloride is typically administered orally and is often prescribed in conjunction with diet and exercise to achieve better glycemic control. Common side effects may include weight gain, edema, and an increased risk of heart failure, necessitating careful patient monitoring. Additionally, it has been associated with potential risks of bladder cancer, leading to specific recommendations regarding its use. Overall, Pioglitazone Hydrochloride plays a significant role in diabetes management, particularly for patients who are insulin-resistant.

Formula:C₁₉H₂₀N₂O₃S・HCl

InChI:InChI=1S/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H

Synonyms:
Pioglitazone HCl
5-[[4-[2-(5-Ethyl-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione N-Oxide
Pioglitazone N-Oxide
5-{4-[2-(5-Ethyl-1-Oxidopyridin-2-Yl)Ethoxy]Benzyl}-1,3-Thiazolidine-2,4-Dione
5-[[4-2-(5-ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-thiazolidinedione Hydrochloride
[5-[[4-[2-(5-Ethyl-2-Pyridinyl)Ethoxy]Phenyl]Methyl]-2,4-] Thiazolidinedione Hydrochloride

Found 5 products.

Product data	Purity	Price range	Estimated delivery
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-1-oxido-2-pyridinyl)ethoxy]phenyl]methyl]- REF: IN-DA001KTLCAS: 145350-09-0	- - -	To inquire	Mon 24 Mar 25
Pioglitazone N-Oxide REF: 4Z-P-107CAS: 145350-09-0	- - -	To inquire	Tue 25 Mar 25
Pioglitazone N-Oxide REF: 86-MM0616.09-0025CAS: 145350-09-0	- - -	941.00 €	Thu 27 Mar 25
Pioglitazone N-Oxide REF: TR-P471010CAS: 145350-09-0	- - -	205.00 €~1,516.00 €	Thu 03 Apr 25
Pioglitazone N-oxide REF: 3D-FP27056CAS: 145350-09-0	Min. 95%	- - -	Discontinued product