CAS 145350-09-0: Pioglitazone Hydrochloride
Description:Pioglitazone Hydrochloride is an antidiabetic medication primarily used to manage type 2 diabetes mellitus. It belongs to the thiazolidinedione class of drugs, which function as agonists of the peroxisome proliferator-activated receptor gamma (PPAR-γ). This action enhances insulin sensitivity in muscle and adipose tissue, thereby improving glucose uptake and utilization. The substance appears as a white to off-white crystalline powder, and it is soluble in water and methanol, which facilitates its formulation in various dosage forms. Pioglitazone Hydrochloride is typically administered orally and is often prescribed in conjunction with diet and exercise to achieve better glycemic control. Common side effects may include weight gain, edema, and an increased risk of heart failure, necessitating careful patient monitoring. Additionally, it has been associated with potential risks of bladder cancer, leading to specific recommendations regarding its use. Overall, Pioglitazone Hydrochloride plays a significant role in diabetes management, particularly for patients who are insulin-resistant.
Formula:C19H20N2O3S・HCl
InChI:InChI=1S/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H
- Synonyms:
- Pioglitazone HCl
- 5-[[4-[2-(5-Ethyl-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione N-Oxide
- Pioglitazone N-Oxide
- 5-{4-[2-(5-Ethyl-1-Oxidopyridin-2-Yl)Ethoxy]Benzyl}-1,3-Thiazolidine-2,4-Dione
- 5-[[4-2-(5-ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-thiazolidinedione Hydrochloride
- [5-[[4-[2-(5-Ethyl-2-Pyridinyl)Ethoxy]Phenyl]Methyl]-2,4-] Thiazolidinedione Hydrochloride

2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-1-oxido-2-pyridinyl)ethoxy]phenyl]methyl]-
Ref: IN-DA001KTL
10mg | To inquire | ||
25mg | To inquire | ||
100mg | To inquire |

Pioglitazone N-Oxide
Ref: 4Z-P-107
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

Pioglitazone N-Oxide
Controlled ProductRef: 86-MM0616.09-0025
25mg | 941.00 € |

Pioglitazone N-Oxide
Controlled ProductRef: TR-P471010
25mg | 1,516.00 € | ||
2500µg | 205.00 € |

Pioglitazone N-oxide
Ref: 3D-FP27056
Undefined size | Discontinued | Request information |