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CAS 145514-04-1

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Amdoxovir

Description:
Amdoxovir, with the CAS number 145514-04-1, is an antiviral compound primarily investigated for its potential in treating HIV infections. It is a nucleoside analog, which means it mimics the structure of natural nucleosides, thereby interfering with viral replication. Amdoxovir exhibits characteristics typical of nucleoside analogs, including the ability to inhibit reverse transcriptase, an enzyme critical for the replication of retroviruses like HIV. The compound is known for its oral bioavailability and has been studied for its efficacy in both treatment and prevention strategies against HIV. Its mechanism of action involves incorporation into viral DNA, leading to chain termination during viral replication. Amdoxovir has shown promise in clinical trials, particularly in patients with drug-resistant strains of HIV. However, like many antiviral agents, it may have side effects and requires careful monitoring during use. Ongoing research continues to evaluate its long-term effectiveness and safety profile in various patient populations.
Formula:C9H12N6O3
InChI:InChI=1S/C9H12N6O3/c10-7-6-8(14-9(11)13-7)15(3-12-6)4-2-17-5(1-16)18-4/h3-5,16H,1-2H2,(H4,10,11,13,14)/t4-,5-/m1/s1
InChI key:InChIKey=RLAHNGKRJJEIJL-RFZPGFLSSA-N
SMILES:NC1=C2C(N(C=N2)[C@@H]3O[C@H](CO)OC3)=NC(N)=N1
Synonyms:
  • 1,3-Dioxolane-2-methanol, 4-(2,6-diamino-9H-purin-9-yl)-, (2R,4R)-
  • DAPD
  • (2R,4R)-4-(2,6-Diamino-9H-purin-9-yl)-1,3-dioxolane-2-methanol
  • β-D-2,6-Diaminopurine-dioxolane
  • 1,3-Dioxolane-2-methanol, 4-(2,6-diamino-9H-purin-9-yl)-, (2R-cis)-
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