CAS 145626-87-5

Bis(2-mercaptoethyl) sulfone

Description:

Bis(2-mercaptoethyl) sulfone, also known by its CAS number 145626-87-5, is an organosulfur compound characterized by the presence of two mercaptoethyl groups attached to a sulfone moiety. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its specific form and purity. It is soluble in polar solvents such as water and alcohols, owing to the presence of the thiol groups, which can engage in hydrogen bonding. The mercaptoethyl groups contribute to its reactivity, allowing it to participate in various chemical reactions, including thiol-disulfide exchange and nucleophilic substitutions. Bis(2-mercaptoethyl) sulfone is often utilized in the synthesis of polymers, as a cross-linking agent, and in the formulation of various chemical products due to its ability to enhance the properties of materials. Additionally, it may exhibit biological activity, making it of interest in medicinal chemistry and materials science. Proper handling and safety precautions are essential due to the potential reactivity of thiol groups.

Formula: C₄H₁₀O₂S₃

InChI: InChI=1/C4H10O2S3/c5-9(6,3-1-7)4-2-8/h7-8H,1-4H2

SMILES: C(CS(=O)(=O)CCS)S

Synonyms:

• 2,2'-Sulfonyldiethanethiol
• Bis(2-mercaptoethyl)sulfone

Ethanethiol, 2,2'-sulfonylbis-

CAS: 145626-87-5

Formula: C₄H₁₀O₂S₃

Color and Shape: Solid

Molecular weight: 186.316

Ref: IN-DA001D94

2,2'-Sulphonyldiethane-1-thiol

CAS: 145626-87-5

2,2'-Sulphonyldiethane-1-thiol

Formula: C₄H₁₀O₂S₃

Purity: ≥95%

Color and Shape: pale yellow solid

Molecular weight: 186.32g/mol

Ref: 54-OR8251T

Bis(2-mercaptoethyl)sulfone

Controlled Product

CAS: 145626-87-5

Stability Air Sensitive, Moisture Sensitive
Applications A useful reagent for the reduction of disulfides in aquous solutions. A superior substitute for DTT.
References Lamoureux, G.V., et al.: J. Org. Chem., 58, 633 (1993), Singh, R., et al.: Protein Sci., 3, suppl 1, 430T (1994)

Formula: C₄H₁₀O₂S₃

Color and Shape: Neat

Molecular weight: 186.32

Ref: TR-B482500

Bis(2-mercaptoethyl)sulfone

CAS: 145626-87-5

Bis(2-mercaptoethyl)sulfone (BMS) is a chemical that can be used to modify the properties of proteins. BMS can be used to increase the solubility of proteins, which can then be purified using liquid chromatography. It also has an extracellular modification capability, which can be activated by adding sodium borohydride or dithiothreitol in order to form a disulfide bond. This reversible reaction is endoplasmic reticulum-dependent and not found in bacteria. BMS binds to DNA with a redox potential of -0.78 V and fluoresces at 564 nm in dimethyl sulfoxide solution. It has been shown to have biochemical properties that are similar to cysteine and glutathione, but does not react with thiols such as mercaptoethanol or glutathione.

Formula: C₄H₁₀O₂S₃

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 186.32 g/mol

Ref: 3D-FB18676