CAS 145645-62-1

no-711 hydrochloride

Description:

No-711 hydrochloride, with the CAS number 145645-62-1, is a chemical compound primarily recognized as a selective inhibitor of the reuptake of the neurotransmitter gamma-aminobutyric acid (GABA). This compound is often studied in the context of neuropharmacology due to its potential effects on GABAergic signaling, which plays a crucial role in regulating neuronal excitability and maintaining the balance between excitation and inhibition in the central nervous system. No-711 hydrochloride is typically characterized by its ability to enhance GABAergic transmission, which may have implications for treating various neurological disorders. In terms of physical properties, it is usually presented as a white to off-white crystalline powder, soluble in water and other polar solvents. Its pharmacological profile suggests that it may influence mood, anxiety, and seizure activity, making it a subject of interest in research related to anxiety disorders and epilepsy. However, as with any pharmacological agent, its use must be carefully evaluated for safety and efficacy in clinical settings.

Formula: C₂₁H₂₃ClN₂O₃

InChI: InChI=1/C21H22N2O3.ClH/c24-21(25)19-12-7-13-23(16-19)14-15-26-22-20(17-8-3-1-4-9-17)18-10-5-2-6-11-18;/h1-6,8-12H,7,13-16H2,(H,24,25);1H

SMILES: c1ccc(cc1)C(=NOCCN1CCC=C(C1)C(=O)O)c1ccccc1.Cl

Synonyms:

• Nnc 711
• 1-(2-(((Diphenylmethylene)amino)oxy)ethyl)-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid
• No 711
• 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-(2-(((diphenylmethylene)amino)oxy)ethyl)-, monohydrochloride
• 1-(2-{[(Diphenylmethylidene)Amino]Oxy}Ethyl)-1,2,5,6-Tetrahydropyridine-3-Carboxylic Acid Hydrochloride (1:1)

NNC-711 (hydrochloride)

CAS: 145645-62-1

Formula: C₂₁H₂₃ClN₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 386.8719

Ref: IN-DA001D8Q

NO-711 hydrochloride

CAS: 145645-62-1

Formula: C₂₁H₂₂N₂O₃·HCl

Molecular weight: 386.87

Ref: 7W-GK7043

NNC 05-711

CAS: 145645-62-1

NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.

Formula: C₂₁H₂₃ClN₂O₃

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 386.87

Ref: TM-T23075