CAS 1456632-41-9

4-[[(4-Cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-N-hydroxybenzamide

Description:

The chemical substance known as 4-[[[4-Cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-N-hydroxybenzamide, with the CAS number 1456632-41-9, is a complex organic compound characterized by its multi-functional structure. It features a hydroxybenzamide moiety, which is indicative of potential biological activity, particularly in medicinal chemistry. The presence of a cyclohexyl group suggests hydrophobic characteristics, while the pentafluorophenyl sulfonyl group introduces significant electronegativity and may enhance the compound's reactivity and solubility in certain solvents. The compound's design indicates potential applications in pharmaceuticals, possibly as an inhibitor or modulator in biochemical pathways. Its intricate structure may also suggest specific interactions with biological targets, making it a candidate for further research in drug development. However, detailed studies on its pharmacokinetics, toxicity, and efficacy would be necessary to fully understand its potential applications and safety profile.

Formula: C₂₉H₂₈F₅N₃O₅S

InChI: InChI=1S/C29H28F5N3O5S/c1-36(43(41,42)28-26(33)24(31)23(30)25(32)27(28)34)16-22(38)37(21-13-11-20(12-14-21)29(39)35-40)15-17-7-9-19(10-8-17)18-5-3-2-4-6-18/h7-14,18,40H,2-6,15-16H2,1H3,(H,35,39)

InChI key: InChIKey=QPSUYVALAOXFGL-UHFFFAOYSA-N

SMILES: N(CC1=CC=C(C=C1)C2CCCCC2)(C(CN(S(=O)(=O)C3=C(F)C(F)=C(F)C(F)=C3F)C)=O)C4=CC=C(C(NO)=O)C=C4

Synonyms:

• Benzamide, 4-[[(4-cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-N-hydroxy-
• 4-[[(4-Cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-N-hydroxybenzamide
• SH5-07 (SH-5-07)
• SH5-07

4-[[(4-Cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-N-hydroxybenzamide

CAS: 1456632-41-9

Formula: C₂₉H₂₈F₅N₃O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 625.6067

Ref: IN-DA01EO6U

SH5-07

CAS: 1456632-41-9

SH5-07

Purity: ≥95%

Molecular weight: 625.61g/mol

Ref: 54-BUP09127

SH5-07

CAS: 1456632-41-9

SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).

Formula: C₂₉H₂₈F₅N₃O₅S

Purity: 95.54%

Color and Shape: Solid

Molecular weight: 625.61

Ref: TM-TQ0052

SH5-07

CAS: 1456632-41-9

SH5-07 is an active analog of the drug survivin. It binds to DNA, inhibiting the synthesis of proteins that are vital for cell division and growth. SH5-07 has been shown to have a strong inhibitory effect on tumor xenografts in mice and human prostate cancer cells.
SH5-07 has also been shown to bind specifically to the DNA binding domains of survivin and inhibit its activity, which may be due to its similarity to the molecule's binding site.

Formula: C₂₉H₂₈F₅N₃O₅S

Purity: Min. 95%

Molecular weight: 625.61 g/mol

Ref: 3D-GIC63241