CAS 145733-36-4
:Tasosartan
Description:
Tasotsartan is an angiotensin II receptor antagonist primarily used in the treatment of hypertension. It belongs to the class of medications known as sartans, which work by blocking the action of angiotensin II, a hormone that constricts blood vessels and increases blood pressure. The chemical formula of tasosartan reflects its complex structure, which includes a biphenyl moiety and a carboxylic acid group, contributing to its pharmacological activity. It is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Tasosartan exhibits good bioavailability and is metabolized in the liver, with its metabolites contributing to its antihypertensive effects. Common side effects may include dizziness, fatigue, and gastrointestinal disturbances, although it is generally well-tolerated. As with other medications in its class, tasosartan is contraindicated in pregnancy due to potential risks to fetal development. Overall, tasosartan represents an important option in the management of high blood pressure, contributing to cardiovascular health.
Formula:C23H21N7O
InChI:InChI=1/C23H21N7O/c1-14-18-11-12-21(31)30(23(18)25-15(2)24-14)13-16-7-9-17(10-8-16)19-5-3-4-6-20(19)22-26-28-29-27-22/h3-10H,11-13H2,1-2H3,(H,26,27,28,29)
InChI key:InChIKey=ADXGNEYLLLSOAR-UHFFFAOYSA-N
SMILES:C(N1C=2C(CCC1=O)=C(C)N=C(C)N2)C3=CC=C(C=C3)C4=C(C=CC=C4)C=5NN=NN5
Synonyms:- 2,4-Dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,6-dihydropyrido[6,5-d]pyrimidin-7-one
- 2,4-dimethyl-8-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one
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Found 8 products.
Pyrido[2,3-d]pyrimidin-7(6H)-one, 5,8-dihydro-2,4-dimethyl-8-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
CAS:Formula:C23H21N7OPurity:99%Color and Shape:SolidMolecular weight:411.45918-((2'-(1H-Tetrazol-5-Yl)-[1,1'-Biphenyl]-4-Yl)Methyl)-2,4-Dimethyl-5,6-Dihydropyrido[2,3-D]Pyrimidin-7(8H)-One
CAS:8-((2'-(1H-Tetrazol-5-Yl)-[1,1'-Biphenyl]-4-Yl)Methyl)-2,4-Dimethyl-5,6-Dihydropyrido[2,3-D]Pyrimidin-7(8H)-OnePurity:95%Molecular weight:411.46g/molTasosartan
CAS:Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).Formula:C23H21N7OPurity:98.2% - 98.9%Color and Shape:SolidMolecular weight:411.46Tasosartan
CAS:<p>Tasosartan is a drug that belongs to the group of angiotensin II receptor antagonists. It is used to treat high blood pressure, congestive heart failure, and to prevent kidney and eye damage caused by diabetes. Tasosartan inhibits the action of an enzyme called angiotensin-converting enzyme (ACE) in the body, which leads to reduced levels of the hormone angiotensin II. This lowers blood pressure by reducing the amount of sodium and water in the body, which decreases blood volume. Tasosartan has been shown to be effective against infectious diseases such as Helicobacter pylori, Mycobacterium tuberculosis, and Chlamydia pneumoniae infections. The drug also has anti-inflammatory effects because it blocks inflammatory cytokines such as IL-1β and TNFα production.</p>Formula:C23H21N7OPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:411.46 g/molTasosartan
CAS:Controlled Product<p>Applications Tasosartan is an angiotensin II receptor antagonist.<br>References Krovat, E., et al.: J. Med. Chem., 46, 716 (2003); Kurup, A., et al.: Chem. Rev., 101, 2727 (2001)<br></p>Formula:C23H21N7OColor and Shape:NeatMolecular weight:411.46
![Pyrido[2,3-d]pyrimidin-7(6H)-one, 5,8-dihydro-2,4-dimethyl-8-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA001DDC.jpg&w=3840&q=75)
![8-((2'-(1H-Tetrazol-5-Yl)-[1,1'-Biphenyl]-4-Yl)Methyl)-2,4-Dimethyl-5,6-Dihydropyrido[2,3-D]Pyrimi…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR1023991.jpg&w=3840&q=75)
