CAS 145940-57-4

(Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH (chicken)

Description:

(Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH (chicken), also known by its CAS number 145940-57-4, is a synthetic analog of the naturally occurring luteinizing hormone-releasing hormone (LHRH). This compound is characterized by specific modifications to its amino acid sequence, which enhance its biological activity and stability compared to the native hormone. The substitution of glycine at position 10 with a des-glycine residue, the incorporation of D-arginine at position 6, and the proline derivative at position 9 contribute to its increased potency and resistance to enzymatic degradation. This peptide is primarily used in research and therapeutic applications related to reproductive health, particularly in the modulation of gonadotropin release. Its structural modifications allow for improved binding affinity to LHRH receptors, making it a valuable tool in studies of hormonal regulation and potential treatments for hormone-sensitive conditions. As with many peptide analogs, its solubility, stability, and bioavailability are critical factors influencing its efficacy in biological systems.

Formula: C₅₈H₈₁N₁₇O₁₃

Synonyms:

• (Des-Gly10,D-Arg6,Pro-Nhet9)-Luteinizing Hormone-Releasing Factor (Chicken)
• (Des-Gly10,D-Arg6,Pro-Nhet9)-Luteinizing Hormone-Releasing Hormone (Chicken)
• (Des-Gly10,D-Arg6,Pro-Nhet9)-Gonadotropin-Releasing Hormone (Chicken)
• (Des-Gly10,D-Arg6,Pro-Nhet9)-Lhrh Ii (Chicken)

(Des-Gly10,D-Arg6,Pro-NHEt 9)-LHRH II (chicken)

CAS: 145940-57-4

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Formula: C₆₄H₇₉N₁₉O₁₂

Purity: Min. 95%

Molecular weight: 1,306.43 g/mol

Ref: 3D-FD109232