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CAS 145986-11-4
:2,4(1H,3H)-Pyrimidinedione,5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)- (9CI)
Description:
2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)-, commonly referred to by its CAS number 145986-11-4, is a synthetic compound that exhibits characteristics typical of nucleoside analogs. This substance features a pyrimidine ring, which is a key structural component in many biological molecules, including nucleic acids. The presence of a fluorine atom at the 5-position enhances its stability and bioactivity, making it a potential candidate for antiviral or anticancer therapies. The oxathiolane moiety contributes to its pharmacological properties, as it mimics the sugar component of nucleotides, facilitating incorporation into nucleic acid structures. The hydroxymethyl group may enhance solubility and interaction with biological targets. Overall, this compound's unique structural features suggest it may play a role in modulating biological processes, particularly in the context of viral replication or cellular proliferation, although specific biological activities would require further investigation.
Formula:C8H9FN2O4S
Synonyms:- 1,3-Oxathiolane,2,4(1H,3H)-pyrimidinedione deriv.
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Found 7 products.
Cis 5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1h,3h)-pyrimidinedione
CAS:Formula:C8H9FN2O4SPurity:95%Color and Shape:SolidMolecular weight:248.2315Emtricitabine Impurity 1
CAS:Formula:C8H9FN2O4SColor and Shape:Off-White SolidMolecular weight:248.235-Fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione
CAS:5-Fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedionePurity:98%Molecular weight:248.23g/molcis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS:Controlled Product<p>Applications Antiviral nucleoside analog, also an impurity found in emtricitabine (E525000).<br>References Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Formula:C8H9FN2O4SColor and Shape:Off-WhiteMolecular weight:248.23cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS:<p>cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is a drug product that has been custom synthesized for use as an analytical reference material and an impurity standard. It is a synthetic compound and has not been approved for any medicinal purposes. The pharmacopoeia it falls under is the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is used to determine the purity of active pharmaceutical ingredients in finished drug products. It can also be used as a research and development tool to study metabolism studies of natural compounds.</p>Formula:C8H9FN2O4SPurity:Min. 95%Molecular weight:248.23 g/mol
![Cis 5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1h,3h)-pyrimidinedione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA001DLC.jpg&w=3840&q=75)
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![cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FFF23363.jpg&w=3840&q=75)
