CAS 146-21-4

10H-Phenothiazine-10-propanamine,N,N-dimethyl-, 5-oxide

Description:

10H-Phenothiazine-10-propanamine, N,N-dimethyl-, 5-oxide, with CAS number 146-21-4, is a chemical compound belonging to the phenothiazine class, which is characterized by a tricyclic structure containing sulfur and nitrogen atoms. This compound features a dimethylamino group and a propanamine side chain, contributing to its unique properties. It is typically recognized for its potential applications in pharmaceuticals, particularly as an antipsychotic and antihistaminic agent. The presence of the 5-oxide functional group indicates that it may exhibit enhanced reactivity or altered pharmacological properties compared to its non-oxidized counterparts. In terms of solubility, compounds in this class often show varying degrees of solubility in organic solvents, with limited water solubility. The compound's stability, reactivity, and biological activity can be influenced by factors such as pH and the presence of other chemical species. Overall, 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, 5-oxide is of interest in medicinal chemistry and pharmacology due to its structural characteristics and potential therapeutic applications.

Formula: C₁₇H₂₀N₂OS

Synonyms:

• Phenothiazine,10-[3-(dimethylamino)propyl]-, 5-oxide (6CI,7CI,8CI)
• Promazine 5-oxide
• Promazine S-oxide
• Promazine sulfoxide
• Propazin sulfoxide
• Propazinesulfoxide
• Skf 5418A

Promazine Sulphoxide 1.0 mg/ml in Methanol

CAS: 146-21-4

Color and Shape: Single Solution

Ref: 61-AMP0290.01-01

Promazine Sulphoxide

CAS: 146-21-4

Color and Shape: Neat

Ref: 61-FOR0290.01

Promazine EP Impurity A

Controlled Product

CAS: 146-21-4

Formula: C₁₇H₂₀N₂OS

Color and Shape: Neat

Molecular weight: 300.42

Ref: 86-MM0290.01

Promazine EP Impurity A

CAS: 146-21-4

Formula: C₁₇H₂₀N₂OS

Molecular weight: 300.43

Ref: 4Z-P-117005

Promazine Sulfoxide

Controlled Product

CAS: 146-21-4

Applications Promazine Sulfoxide is a metabolite of Chlorpromazine (C424750) and an impurity of Promazine (P756300). Both Chlorpromazine and Promazine are antipsychotic drugs.
References Zhang, S., et al.: Fenxi Ceshi Xuebao, 30, 1088 (2011); Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990); Banci, L., et al.: Biochemistry, 38, 3205 (1999), Lawal, O., et al.: Food Chemi., 87, 205 (2004); Shleev, S., et al.: Bioorg. Chem., 35, 35 (2007);

Formula: C₁₇H₂₀N₂OS

Color and Shape: Light Yellow

Molecular weight: 300.42

Ref: TR-P756310

Promazine EP Impurity A

CAS: 146-21-4

Formula: C₁₇H₂₀N₂OS

Molecular weight: 300.42

Ref: ST-EA-CP-P136005