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CAS 146-54-3

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Triflupromazine

Description:
Triflupromazine is a phenothiazine derivative primarily used as an antipsychotic medication. It exhibits a range of pharmacological properties, including sedative and antiemetic effects. The chemical structure of triflupromazine features a trifluroethyl group, which enhances its potency and efficacy. It acts primarily by antagonizing dopamine receptors in the central nervous system, which is a common mechanism among antipsychotic drugs. Triflupromazine is typically administered in its hydrochloride salt form and is known for its relatively long half-life, allowing for less frequent dosing. The substance is also characterized by its lipophilicity, which facilitates its ability to cross the blood-brain barrier. Common side effects may include sedation, dry mouth, and potential extrapyramidal symptoms, which are typical of many antipsychotic medications. Due to its sedative properties, it may also be used in the management of anxiety and agitation. As with all medications, careful consideration of dosage and monitoring for adverse effects is essential in clinical use.
Formula:C18H19F3N2S
InChI:InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3
InChI key:InChIKey=XSCGXQMFQXDFCW-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(SC=3C1=CC=CC3)=CC=C(C(F)(F)F)C2
Synonyms:
  • 10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)phenothiazine
  • 2-(Trifluoromethyl)promazine
  • Fluopromazine
  • N,N-Dimethyl-2-(trifluoromethyl)-10H-phenothiazine-10-propanamine
  • Phenothiazine, 10-[3-(dimethylamino)propyl]-2-(trifluoromethyl)-
  • Psyquil
  • Siquil
  • Trifluopromazine
  • Triflupromazin
  • Triflupromazina
  • See more synonyms
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