CAS 146-54-3: Triflupromazine

Description: Triflupromazine is a phenothiazine derivative primarily used as an antipsychotic medication. It exhibits a range of pharmacological properties, including sedative and antiemetic effects. The chemical structure of triflupromazine features a trifluroethyl group, which enhances its potency and efficacy. It acts primarily by antagonizing dopamine receptors in the central nervous system, which is a common mechanism among antipsychotic drugs. Triflupromazine is typically administered in its hydrochloride salt form and is known for its relatively long half-life, allowing for less frequent dosing. The substance is also characterized by its lipophilicity, which facilitates its ability to cross the blood-brain barrier. Common side effects may include sedation, dry mouth, and potential extrapyramidal symptoms, which are typical of many antipsychotic medications. Due to its sedative properties, it may also be used in the management of anxiety and agitation. As with all medications, careful consideration of dosage and monitoring for adverse effects is essential in clinical use.

Formula: C₁₈H₁₉F₃N₂S

InChI: InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3

InChI key: InChIKey=XSCGXQMFQXDFCW-UHFFFAOYSA-N

SMILES: FC(F)(F)C1=CC=C2SC=3C=CC=CC3N(C2=C1)CCCN(C)C

Synonyms:

• 10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)phenothiazine
• 2-(Trifluoromethyl)promazine
• Fluopromazine
• N,N-Dimethyl-2-(trifluoromethyl)-10H-phenothiazine-10-propanamine
• Phenothiazine, 10-[3-(dimethylamino)propyl]-2-(trifluoromethyl)-
• Psyquil
• Siquil
• Trifluopromazine
• Triflupromazin
• Triflupromazina
• Triflupromazine
• 10H-Phenothiazine-10-propanamine, N,N-dimethyl-2-(trifluoromethyl)-
• dimethyl(3-(2-trifluoromethylphenothiazin-10-yl)propyl)amine

Triflupromazine Hydrochloride

CAS: 1098-60-8 146-54-3

• Formula: C₁₈H₁₉F₃N₂S·HCl
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 388.88

Triflupromazine

CAS: 146-54-3

Triflupromazine is a phenothiazine drug used as an antipsychotic and antiemetic.

• Formula: C₁₈H₁₉F₃N₂S
• Color and Shape: Solid
• Molecular weight: 352.42

N,N-Dimethyl-3-[2-(Trifluoromethyl)Phenothiazin-10-Yl]Propan-1-Amine

CAS: 146-54-3

Phenothiazine is a chemical that is used as an antipsychotic drug. It has been shown …

• Formula: C₁₈H₁₉F₃N₂S
• Purity: Min. 95%
• Molecular weight: 352.42 g/mol