CAS 14605-22-2: Tauroursodeoxycholic acid
Description:Tauroursodeoxycholic acid (TUDCA) is a bile acid derivative that plays a significant role in various biological processes. It is a taurine-conjugated form of ursodeoxycholic acid, which is known for its cytoprotective properties. TUDCA is characterized by its hydrophilic nature, which enhances its solubility in water compared to other bile acids. This compound is primarily involved in the regulation of bile flow and has been studied for its potential therapeutic effects in liver diseases, neurodegenerative disorders, and metabolic syndromes. TUDCA is believed to exert its beneficial effects through mechanisms such as anti-apoptotic activity, modulation of endoplasmic reticulum stress, and improvement of mitochondrial function. Additionally, it has been investigated for its role in promoting insulin sensitivity and reducing inflammation. TUDCA is typically administered in a clinical setting or as a dietary supplement, and its safety profile is generally favorable, although further research is ongoing to fully elucidate its mechanisms and therapeutic potential.
Formula:C26H45NO6S
InChI:InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-/m1/s1
InChI key:InChIKey=BHTRKEVKTKCXOH-LBSADWJPSA-N
SMILES:O=C(NCCS(=O)(=O)O)CCC(C)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C
- Synonyms:
- 2-(3Α,7Β-Dihydroxy-5Β-Cholan-24-Amido)Ethanesulfonic Acid
- 2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic acid
- 2-{[(3Alpha,5Beta,7Beta)-3,7-Dihydroxy-24-Oxocholan-24-Yl]Amino}Ethanesulfonic Acid
- 2-{[(3Alpha,5Beta,7Beta,8Xi,9Xi,14Xi)-3,7-Dihydroxy-24-Oxocholan-24-Yl]Amino}Ethanesulfonic Acid
- 3α,7β-Dihydroxy-5β-cholanoyltaurine
- 9,10-Secocholesta-5,7,10-Trien-3-Ol
- Cholane, ethanesulfonic acid deriv.
- Ethanesulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
- Taurine, N-(3α,7β-dihydroxy-5β-cholan-24-oyl)-
- Taurolite
- See more synonyms
- Taurursodiol
- Ur 906
- Ursodeoxycholyltaurine
- Ursodoxicoltaurine
- Tauroursodeoxycholic acid