CAS 14605-22-2

Tauroursodeoxycholic acid

Description:

Tauroursodeoxycholic acid (TUDCA) is a bile acid derivative that plays a significant role in various biological processes. It is a taurine-conjugated form of ursodeoxycholic acid, which is known for its cytoprotective properties. TUDCA is characterized by its hydrophilic nature, which enhances its solubility in water compared to other bile acids. This compound is primarily involved in the regulation of bile flow and has been studied for its potential therapeutic effects in liver diseases, neurodegenerative disorders, and metabolic syndromes. TUDCA is believed to exert its beneficial effects through mechanisms such as anti-apoptotic activity, modulation of endoplasmic reticulum stress, and improvement of mitochondrial function. Additionally, it has been investigated for its role in promoting insulin sensitivity and reducing inflammation. TUDCA is typically administered in a clinical setting or as a dietary supplement, and its safety profile is generally favorable, although further research is ongoing to fully elucidate its mechanisms and therapeutic potential.

Formula: C₂₆H₄₅NO₆S

InChI: InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-/m1/s1

InChI key: InChIKey=BHTRKEVKTKCXOH-LBSADWJPSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCCS(=O)(=O)O)=O)C)[H])[H]

Synonyms:

• 2-(3Α,7Β-Dihydroxy-5Β-Cholan-24-Amido)Ethanesulfonic Acid
• 2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic acid
• 2-{[(3Alpha,5Beta,7Beta)-3,7-Dihydroxy-24-Oxocholan-24-Yl]Amino}Ethanesulfonic Acid
• 2-{[(3Alpha,5Beta,7Beta,8Xi,9Xi,14Xi)-3,7-Dihydroxy-24-Oxocholan-24-Yl]Amino}Ethanesulfonic Acid
• 3α,7β-Dihydroxy-5β-cholanoyltaurine
• 9,10-Secocholesta-5,7,10-Trien-3-Ol
• Cholane, ethanesulfonic acid deriv.
• Ethanesulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
• Taurine, N-(3α,7β-dihydroxy-5β-cholan-24-oyl)-
• Taurolite
• Taurursodiol
• Ur 906
• Ursodeoxycholyltaurine
• Ursodoxicoltaurine

Tauroursodeoxycholic Acid Dihydrate

CAS: 14605-22-2

Formula: C₂₆H₄₅NO₆S·2H₂O

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 535.74

Ref: 3B-T1567

URSODOXICOLTAURINE FOR IMPURITY B IDENTIFICATION CRS

CAS: 14605-22-2

URSODOXICOLTAURINE FOR IMPURITY B IDENTIFICATION CRS

Ref: 41-Y0002449

Ethanesulfonic acid,2-[[(3a,5b,7b)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-

CAS: 14605-22-2

Formula: C₂₆H₄₅NO₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 499.7036

Ref: IN-DA00HXH5

Sodium tauroursodeoxycholate

CAS: 14605-22-2

Formula: C₂₆H₄₄NO₆SNa·xH₂O

Purity: ≥ 97.0% (dried basis)

Color and Shape: White or almost white powder

Molecular weight: 521.69 (anhydrous)

Ref: 7W-GK8560

Tauroursodeoxycholate

CAS: 14605-22-2

Tauroursodeoxycholate

Purity: ≥98%

Molecular weight: 499.7g/mol

Ref: 54-BUP14868

Tauroursodeoxycholic Acid (TUDCA)

CAS: 14605-22-2

Formula: C₂₆H₄₅NO₆S

Color and Shape: White To Off-White Solid

Molecular weight: 499.71

Ref: 4Z-T-282

Tauroursodeoxycholic acid

CAS: 14605-22-2

Tauroursodeoxycholic acid

Purity: 98%

Molecular weight: 499.71g/mol

Ref: 54-OR1029762

Tauroursodeoxycholate

CAS: 14605-22-2

Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.

Formula: C₂₆H₄₅NO₆S

Purity: 98.77% - 99.93%

Color and Shape: White Solid

Molecular weight: 499.7

Ref: TM-T2532

Tauro-d4-ursodeoxycholic Acid

Controlled Product

CAS: 14605-22-2

Applications Tauro-d4-ursodeoxycholic Acid is a useful isotopically labeled compound of Tauroursodeoxycholic Acid (T779310). It is used in studying regaining functionality capacity for stem cell or fibroblast cell and functional lines used in cellular therapy.
References Teker, Hikmet Taner, et al.: Turk. Pat. Appl., (2019);

Formula: C₂₆H₄₁D₄NO₆S

Color and Shape: Off-White

Molecular weight: 503.73

Ref: TR-T779312

Tauroursodeoxycholic Acid

CAS: 14605-22-2

Stability Hygroscopic
Applications TAUROURSODEOXYCHOLIC ACID (cas# 14605-22-2) is a useful research chemical.

Formula: C₂₆H₄₅NO₆S

Color and Shape: Off-White

Molecular weight: 499.70

Ref: TR-T779310

Tauroursodeoxycholic acid

CAS: 14605-22-2

Tauroursodeoxycholic acid (TUDCA) is a bile acid derivative, which is synthesized endogenously in the human body as a liver metabolite. It originates from the conjugation of ursodeoxycholic acid (UDCA) with taurine, which enhances its solubility and biological activity. TUDCA functions primarily by inhibiting apoptosis and reducing endoplasmic reticulum stress within cells. It achieves this by mitigating the accumulation of misfolded proteins and enhancing proper protein folding, thereby maintaining cellular homeostasis.

Formula: C₂₆H₄₅NO₆S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 499.7 g/mol

Ref: 3D-FT03670

Tauroursodeoxycholate

CAS: 14605-22-2

Purity: 98%

Molecular weight: 499.297

Ref: 10-F811909

Tauroursodeoxycholic Acid

CAS: 14605-22-2

Formula: C₂₆H₄₅NO₆S

Molecular weight: 499.71

Ref: ST-EA-CP-U1020