CAS 146062-45-5

5-[[4-[2-(5-ACETYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL]-2,4THIAZOLIDINEDIONE

Description:

5-[[4-[2-(5-Acetyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, identified by its CAS number 146062-45-5, is a synthetic organic compound characterized by its thiazolidinedione core, which is known for its role in pharmacology, particularly in the treatment of diabetes. The structure features a thiazolidinedione ring, which is a five-membered heterocyclic compound containing sulfur and nitrogen, contributing to its biological activity. The presence of an acetyl group and a pyridine moiety enhances its lipophilicity and potential interactions with biological targets. This compound may exhibit properties such as anti-inflammatory and insulin-sensitizing effects, making it of interest in medicinal chemistry. Its complex structure suggests potential for diverse reactivity and interactions, which can be explored in drug development. As with many thiazolidinediones, it may also be subject to specific regulatory considerations due to its pharmacological implications. Overall, this compound represents a significant area of research in the context of metabolic diseases and therapeutic agents.

Formula: C₁₉H₁₈N₂O₄S

InChI: InChI=1/C19H18N2O4S/c1-12(22)14-4-5-15(20-11-14)8-9-25-16-6-2-13(3-7-16)10-17-18(23)21-19(24)26-17/h2-7,11,17H,8-10H2,1H3,(H,21,23,24)

SMILES: CC(=O)c1ccc(CCOc2ccc(cc2)CC2C(=NC(=O)S2)O)nc1

Synonyms:

• Keto-Pioglitazone (M-III)
• Keto Pioglitazone
• Pioglitazone, ketone
• 5-{4-[2-(5-Acetylpyridin-2-Yl)Ethoxy]Benzyl}-1,3-Thiazolidine-2,4-Dione
• Keto PioglitazoneSee product # K200600
• Keto Pioglitazone Discontinued see product # K200600

Pioglitazone Ketone

CAS: 146062-45-5

Formula: C₁₉H₁₈N₂O₄S

Color and Shape: Solid

Molecular weight: 370.4222

Ref: IN-DA001DN0

Pioglitazone Ketone (M-III)

CAS: 146062-45-5

Formula: C₁₉H₁₉N₂O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 370.42

Ref: 4Z-P-102

Ketopioglitazone

CAS: 146062-45-5

Ketopioglitazone is an active metabolite of pioglitazone.

Formula: C₁₉H₁₈N₂O₄S

Color and Shape: Solid

Molecular weight: 370.42

Ref: TM-T20465

Keto Pioglitazone (M-III)

Controlled Product

CAS: 146062-45-5

Applications A metabolite of Pioglitazone (P471000).
References Tanis, S.P., et al.: J. Med. Chem., 39, 5053 (1996)

Formula: C₁₉H₁₈N₂O₄S

Color and Shape: Neat

Molecular weight: 370.42

Ref: TR-K200600

Keto pioglitazone (M-III)

CAS: 146062-45-5

Keto pioglitazone (M-III) is a chromatographic method for the determination of pioglitazone in ovary granuloma. This method uses ammonium formate as an eluent and is based on liquid chromatography with tandem mass spectrometry detection (LC-MS/MS). Keto pioglitazone (M-III) has been used to diagnose ovarian granulomas that are characteristic of chronic inflammation, such as those associated with autoimmune diseases. The clinical response to keto pioglitazone (M-III) has not been established.

Formula: C₁₉H₁₈N₂O₄S

Purity: Min. 95%

Molecular weight: 370.42 g/mol

Ref: 3D-FK24782

Pioglitazone M3 Metabolite

CAS: 146062-45-5

Formula: C₁₉H₂₀N₂O₄S

Molecular weight: 372.4

Ref: ST-EA-CP-P7025