CAS 1461-15-0: Calcein

Description: Calcein is a fluorescent dye commonly used in biological and chemical applications, particularly in microscopy and cell imaging. It is characterized by its bright green fluorescence, which is emitted when excited by specific wavelengths of light. The chemical structure of calcein includes multiple carboxyl groups, contributing to its solubility in water and making it suitable for various aqueous environments. Its molecular formula is C27H22N2O7, and it has a relatively high molar absorptivity, enhancing its utility in fluorescence-based assays. Calcein is often utilized as a viability stain in live/dead cell assays, as it can penetrate live cells and emit fluorescence, while non-viable cells do not retain the dye. Additionally, calcein can chelate metal ions, which allows it to be used in studies involving metal ion detection and quantification. Overall, calcein's stability, solubility, and fluorescent properties make it a valuable tool in both research and clinical settings.

Formula: C₃₀H₂₆N₂O₁₃

InChI: InChI=1S/C30H26N2O13/c33-21-7-23-19(5-15(21)9-31(11-25(35)36)12-26(37)38)30(18-4-2-1-3-17(18)29(43)45-30)20-6-16(22(34)8-24(20)44-23)10-32(13-27(39)40)14-28(41)42/h1-8,33-34H,9-14H2,(H,35,36)(H,37,38)(H,39,40)(H,41,42)

InChI key: InChIKey=DEGAKNSWVGKMLS-UHFFFAOYSA-N

SMILES: O=C(O)CN(CC(=O)O)CC=1C=C2C(OC3=CC(O)=C(C=C3C42OC(=O)C=5C=CC=CC54)CN(CC(=O)O)CC(=O)O)=CC1O

Synonyms:

• 2,2',2'',2'''-[(3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-2',7'-diyl)bis(methanediylnitrilo)]tetraacetic acid
• 2,2′,2′′,2′′′-(((3′,6′-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-2′,7′-diyl)bis(methylene))bis(azanetriyl))tetraacetic acid
• 2,7-Bis[N,N-bis(carboxymethyl)aminomethylene]fluorescein
• 2-[[7′-[[Bis(carboxymethyl)amino]methyl]-3′,6′-dihydroxy-3-oxospiro[2-benzofuran-1,9′-xanthene]-2′-yl]methyl-(carboxymethyl)amino]acetic acid
• Acetic acid, [(3′,6′-dihydroxy-2′,7′-fluorandiyl)bis(methylenenitrilo)]tetra-
• Fluorescein complexon
• Fluorescein, 2′,7′-bis[[bis(carboxymethyl)amino]methyl]-
• Fluorexon
• Glycine, N,N′-[(3′,6′-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-2′,7′-diyl)bis(methylene)]bis[N-(carboxymethyl)-
• N,N′-[(3′,6′-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-2′,7′-diyl)bis(methylene)]bis[N-(carboxymethyl)glycine]
• NSC 298193
• Oftasceine
• Spiro[isobenzofuran-1(3H),9′-[9H]xanthene], glycine deriv.

Calcein (mixture of isomers) [for Fluorometric Determination of Ca]

CAS: 1461-15-0154071-48-4

• Formula: C₃₀H₂₆N₂O₁₃
• Color and Shape: Orange to Brown powder to crystaline
• Molecular weight: 622.54

Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)-

CAS: 1461-15-0

• Formula: C₃₀H₂₆N₂O₁₃
• Color and Shape: Solid
• Molecular weight: 622.5330400000001

Calcein

CAS: 1461-15-0

Calcein is a fluorescent dye for detecting lipid vesicle leaks and calcium titration with EDTA.

• Formula: C₃₀H₂₆N₂O₁₃
• Purity: ≥98%
• Color and Shape: Orange Powder
• Molecular weight: 622.53

Fluorexon

CAS: 1461-15-0

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₃₀H₂₆N₂O₁₃
• Color and Shape: Yellow to orange-brown, Powder
• Molecular weight: 622.54

Calcein (mixture of isomers)

CAS: 1461-15-0

• Purity: 95.0%
• Color and Shape: Solid, Yellow powder
• Molecular weight: 622.5390014648438

Fluorexon

CAS: 1461-15-0

Fluorexon is a novel fluorogenic probe that can be used as an optical sensor to …

• Formula: C₃₀H₂₆N₂O₁₃
• Color and Shape: Yellow Powder
• Molecular weight: 622.53 g/mol

Calcein

CAS: 1461-15-0

Applications Calcein (cas# 1461-15-0) is a useful research chemical.

• Formula: C₃₀H₂₆N₂O₁₃
• Color and Shape: Neat
• Molecular weight: 622.53

Calcein Reagent extrapure AR (Fluorescein Complexone)

CAS: 1461-15-0

• Formula: C₃₀H₂₆N₂O₁₃
• Color and Shape: Yellow to orange, Crystalline powder
• Molecular weight: 622.50