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CAS 14611-52-0

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Selegiline hydrochloride

Description:
Selegiline hydrochloride is a selective monoamine oxidase B (MAO-B) inhibitor primarily used in the treatment of Parkinson's disease and major depressive disorder. It is a white to off-white crystalline powder that is soluble in water and exhibits a melting point that indicates its stability under standard conditions. The chemical formula of selegiline hydrochloride reflects its structure, which includes a phenethylamine backbone with a propargyl group, contributing to its pharmacological activity. As an MAO-B inhibitor, it works by preventing the breakdown of dopamine in the brain, thereby enhancing dopaminergic activity, which is beneficial in managing symptoms of Parkinson's disease. Selegiline is also known for its potential neuroprotective effects and may have applications in treating cognitive decline. It is typically administered orally and can be found in various formulations, including tablets and transdermal patches. However, it is essential to monitor for possible interactions with other medications, particularly those affecting serotonin levels, due to the risk of serotonin syndrome.
Formula:C13H17N·ClH
InChI:InChI=1S/C13H17N.ClH/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13;/h1,5-9,12H,10-11H2,2-3H3;1H/t12-;/m1./s1
InChI key:InChIKey=IYETZZCWLLUHIJ-UTONKHPSSA-N
SMILES:C([C@H](N(CC#C)C)C)C1=CC=CC=C1.Cl
Synonyms:
  • (-)-Deprenil hydrochloride
  • (-)-Deprenyl hydrochloride
  • (R)-N-Methyl-N-(1-phenylpropan-2-yl)prop-2-yn-1-amine hydrochloride
  • Benzeneethanamine, N,α-dimethyl-N-2-propyn-1-yl-, hydrochloride (1:1), (αR)-
  • Benzeneethanamine, N,α-dimethyl-N-2-propynyl-, hydrochloride, (R)-
  • Benzeneethanamine, N,α-dimethyl-N-2-propynyl-, hydrochloride, (αR)-
  • Eldeprine
  • Eldepryl
  • FP Tablet 2.5
  • Jumex
  • See more synonyms
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