As of my last update in October 2023, "Aftin-5" with the CAS number 1461717-05-4 is not widely recognized in the scientific literature or databases, which may indicate that it is a relatively new or specialized compound. Typically, compounds like this may be associated with specific applications in fields such as pharmaceuticals, agrochemicals, or materials science. Characteristics of chemical substances generally include their molecular structure, solubility, stability, reactivity, and potential biological activity. For a comprehensive understanding, one would typically refer to specific studies or data sheets that detail its physical and chemical properties, such as melting point, boiling point, and spectral data. If "Aftin-5" is under investigation or development, its characteristics may be documented in proprietary research or patent filings. For accurate and detailed information, consulting scientific literature or databases that specialize in chemical substances would be essential.

Aftin-5

1461717-05-4: As of my last update in October 2023, "Aftin-5" with the CAS number 1461717-05-4 is not widely recognized in the scientific literature or databases, which may indicate that it is a relatively new or specialized compound. Typically, compounds like this may be associated with specific applications in fields such as pharmaceuticals, agrochemicals, or materials science. Characteristics of chemical substances generally include their molecular structure, solubility, stability, reactivity, and potential biological activity. For a comprehensive understanding, one would typically refer to specific studies or data sheets that detail its physical and chemical properties, such as melting point, boiling point, and spectral data. If "Aftin-5" is under investigation or development, its characteristics may be documented in proprietary research or patent filings. For accurate and detailed information, consulting scientific literature or databases that specialize in chemical substances would be essential.

<p>Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.</p>

CAS 1461717-05-4

Aftin-5

Aftin-5

Ref: TM-T88257