CAS 14622-47-0

16β-METHYL EPOXIDE(DB-11), 17α,21-DIHYDROXY-9β,11β,EPOXY-16β-METHYLPREGN-1,4-DIENE-3,20-DIONE

Description:

16β-Methyl Epoxide (DB-11) is a synthetic steroid compound characterized by its complex structure, which includes multiple functional groups such as hydroxyl (-OH) and epoxy groups. This compound is derived from the pregnane steroid framework, featuring a methyl group at the 16β position and an epoxy group at the 9β,11β positions. The presence of hydroxyl groups at the 17α and 21 positions contributes to its potential biological activity, influencing its interaction with steroid receptors. The compound is primarily studied for its pharmacological properties, particularly in the context of its potential therapeutic applications in hormone-related conditions. Its unique structural features may also affect its solubility, stability, and metabolic pathways. As with many steroid derivatives, the biological effects of 16β-Methyl Epoxide can vary significantly based on its stereochemistry and the specific biological systems it interacts with. Safety and efficacy assessments are crucial for any potential applications in medicine or research.

Synonyms:

• 16Beta-Methyl Epoxide(Db-11): 17Alpha,21-Dihydroxy-9Beta,11Beta,Epoxy-16Beta-Methylpregn-1,4-Diene-3,20-Dione

Dexamethasone EP Impurity I

CAS: 14622-47-0

Formula: C₂₂H₂₈O₅

Color and Shape: White To Off-White Solid

Molecular weight: 372.46

Ref: 4Z-D-3613

(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione

CAS: 14622-47-0

Applications (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, can be used for the synthesis of Calicoferol E, a vitamin D3 analogues.
References Vir Singh, T., et al.: ARKAT USA, INc., (2002);

Formula: C₂₂H₂₈O₅

Color and Shape: White To Light Red

Molecular weight: 372.45

Ref: TR-E589170

Dexamethasone EP Impurity I

CAS: 14622-47-0

Dexamethasone EP Impurity I is a metabolite of dexamethasone. It is produced by microbial transformation and can be produced in vivo from the metabolites of dexamethasone. It has been shown to have anti-inflammatory properties, which are due to its ability to inhibit prostaglandin synthesis. Dexamethasone EP Impurity I is a carbanion that reacts with electron-rich functional groups such as hydroxyl and amine groups. This reaction creates an enolate intermediate, which undergoes protonation to form a betamethasone derivative. The chromatographic technique used for separation is based on the polarity of the solute and the stationary phase, which allows for the separation of this impurity from other compounds with different chemical properties.

Formula: C₂₂H₂₈O₅

Purity: Min. 95%

Molecular weight: 372.45 g/mol

Ref: 3D-ID179385

Dexamethasone EP Impurity I

CAS: 14622-47-0

Formula: C₂₂H₂₈O₅

Molecular weight: 372.46

Ref: ST-EA-CP-D17008