CAS 146275-18-5: trans-3'-Hydroxycotinine-N-b-D-glucuronide

Description:Trans-3'-Hydroxycotinine-N-b-D-glucuronide is a metabolite of nicotine, specifically a glucuronide conjugate of 3'-hydroxycotinine, which is a primary metabolite of nicotine in the human body. This compound is characterized by its glucuronidation, a biochemical process that involves the addition of glucuronic acid to a substrate, enhancing its solubility and facilitating excretion. The structure of trans-3'-Hydroxycotinine-N-b-D-glucuronide includes a hydroxyl group and a glucuronide moiety, which contribute to its polar nature. This polar characteristic is significant for its pharmacokinetics, as it influences the compound's absorption, distribution, metabolism, and excretion. The compound is primarily studied in the context of nicotine metabolism and its implications for tobacco use and dependence. Its presence in biological samples can serve as a biomarker for nicotine exposure. Overall, trans-3'-Hydroxycotinine-N-b-D-glucuronide plays a crucial role in understanding the metabolic pathways of nicotine and its effects on human health.

Formula:C₁₆H₂₀N₂O₈

InChI:InChI=1/C16H20N2O8/c1-18-8(7-3-2-4-17-6-7)5-9(14(18)22)25-16-12(21)10(19)11(20)13(26-16)15(23)24/h2-4,6,8-13,16,19-21H,5H2,1H3,(H,23,24)

Synonyms:
trans-3-Hydroxycotinine glucuronide
1-Methyl-2-Oxo-5-(Pyridin-3-Yl)Pyrrolidin-3-Yl Hexopyranosiduronic Acid

Found 4 products.

Product data	Purity	Price range	Estimated delivery
N-(trans-3-Hydroxycotinine)-b-D-glucuronide REF: 7W-GC7509CAS: 146275-18-5	- - -	To inquire	Fri 28 Mar 25
trans-3'-Hydroxy Cotinine N-β-D-Glucuronide REF: TR-H924530CAS: 146275-18-5	- - -	1,249.00 €~5,045.00 €	Tue 08 Apr 25
trans-3'-Hydroxy Cotinine-d3 N-Beta-D-Glucuronide REF: TR-H924535CAS: 146275-18-5	- - -	1,919.00 €	Tue 08 Apr 25
N-(trans-3-Hydroxycotinine)-b-D-glucuronide REF: 3D-MH07435CAS: 146275-18-5	Min. 95%	1,031.00 €~4,536.00 €	Thu 08 May 25