CAS 1463-10-1

5-Methyluridine

Description:

5-Methyluridine, also known as ribothymidine, is a nucleoside that consists of the pyrimidine base uracil with a methyl group attached to the 5-position of the uracil ring. This modification enhances the stability and functionality of RNA molecules, particularly in the context of tRNA, where it plays a role in the proper folding and function of the molecule. The chemical formula of 5-Methyluridine is C10H13N2O5, and it is characterized by its ability to participate in hydrogen bonding due to the presence of hydroxyl and amino groups. This compound is soluble in water and exhibits a relatively low melting point. 5-Methyluridine is of interest in biochemical research and has potential applications in the fields of molecular biology and pharmacology, particularly in the study of RNA modifications and their effects on gene expression and protein synthesis. Its CAS number, 1463-10-1, is used for identification in chemical databases and regulatory contexts.

Formula: C₁₀H₁₄N₂O₆

InChI: InChI=1/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6+,7?,9-/m1/s1

InChI key: InChIKey=DWRXFEITVBNRMK-JXOAFFINSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(C)=C2

Synonyms:

• 1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-dihydropyrimidine-2,4-dione
• 1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosylthymine
• 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5-Me-U
• 5-Methyl-Uridine
• 5-methyl-1-(beta-L-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 5-methyl-1-[(2xi)-beta-D-threo-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
• 5-methyl-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
• Ribosylthymine
• Ribothymidine
• Thymine riboside
• Uridine, 5-methyl-
• β-<span class="text-smallcaps">D</span>-Ribofuranoside, thymine-1
• 5-Methyluridine
• 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-D-ribofuranosyl-
• 5-methyuridine
• BETA-RIBOFURANOSIDE
• ribosylthymine/5-methyluridine
• 1-(BETA-D-RIBOFURANOSYL)THYMINE
• 1-β-D-Ribofuranosylthymine
• 5-methyluridine/ribothymidine
• 5-METHYL-D-URIDINE
• 5-Methyluridine (Patent )
• 5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL
• 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• Methyluridine
• 5-methyl-uridin
• THYMINERIBOSIDE
• BETA-D-THYMINE RIBOSIDE
• 1-(BETA-D-RIBOFURANOSYL)THYMIDINE

5-Methyluridine

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 258.23

Ref: 3B-M1405

5-Methyluridine, 99%

CAS: 1463-10-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₄N₂O₆

Purity: 99%

Molecular weight: 258.23

Ref: 02-H64259

Uridine, 5-methyl-

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 258.2280

Ref: IN-DA001DVT

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine

Purity: ≥98%

Molecular weight: 258.23g/mol

Ref: 54-BUP18363

5-Methyluridine

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Molecular weight: 258.23

Ref: 7W-GE5148

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine

Formula: C₁₀H₁₄N₂O₆

Purity: 97%

Color and Shape: white solid

Molecular weight: 258.23g/mol

Ref: 54-OR52639

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine, a methylated nucleoside in human fluids, is higher in tumor patients; targeted by hypomethylating drugs in cancer therapy.

Formula: C₁₀H₁₄N₂O₆

Purity: 99.72%

Color and Shape: Solid

Molecular weight: 258.23

Ref: TM-T5282

5-Methyluridine

CAS: 1463-10-1

Applications A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.
References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),

Formula: C₁₀H₁₄N₂O₆

Color and Shape: Neat

Molecular weight: 258.23

Ref: TR-M338190

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine is a nucleoside that is used to inhibit the replication of cells. It is also used for the treatment of cancer, infectious diseases, and other conditions. 5-Methyluridine inhibits cellular replication by binding to ribothymidine and uridine in the nucleus. The inhibition of cellular proliferation is due to a lack of dna synthesis and RNA synthesis. This nucleoside has been shown to have inhibitory properties against mouse tumor cells grown in vitro, as well as the wild-type strain grown in vivo. 5-Methyluridine may be useful for the treatment of cancer tissues because it can suppress the growth of tumors by inhibiting their ability to replicate.

Formula: C₁₀H₁₄N₂O₆

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 258.23 g/mol

Ref: 3D-NM04922

5-Methyluridine

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Purity: 95%

Color and Shape: Solid, White to almost white crystal powder

Molecular weight: 258.23

Ref: 10-F212233

5-Methyluridine extrapure, 98%

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Purity: min. 98%

Color and Shape: White to off - white, Crystalline powder, Clear, Colourless

Molecular weight: 258.23

Ref: SR-77337

5-Methyluridine

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Molecular weight: 258.23

Ref: ST-EA-CP-Z6011