CAS 146328-85-0

5-Bromo-2-fluorobenzoic acid

Description:

5-Bromo-2-fluorobenzoic acid is an aromatic carboxylic acid characterized by the presence of both bromine and fluorine substituents on the benzene ring. The bromine atom is located at the 5-position, while the fluorine atom is at the 2-position relative to the carboxylic acid group. This compound typically appears as a white to off-white solid and is soluble in organic solvents, with limited solubility in water due to its hydrophobic aromatic structure. It exhibits acidic properties due to the carboxylic acid functional group, allowing it to participate in various chemical reactions, including esterification and nucleophilic substitution. The presence of halogens can influence its reactivity, making it a useful intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Additionally, its unique substitution pattern may impart specific electronic and steric effects, which can be exploited in designing compounds with desired biological activities. Safety precautions should be taken when handling this compound, as with many halogenated organic substances.

Formula: C₇H₄BrFO₂

InChI: InChI=1S/C7H4BrFO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,(H,10,11)

InChI key: InChIKey=PEXAZYDITWXYNJ-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(F)C=CC(Br)=C1

Synonyms:

• 2-Fluoro-5-Bromobenzoic Acid
• 5-Bromo-2-Fluoro-Benzoic Acid
• 5-Bromo-2-Fluorobenzoate
• 5-Bromo-2-fluorobenzoicacid
• Benzoic acid, 5-bromo-2-fluoro-
• Buttpark 19\01-67
• Rarechem Al Bo 0757
• 5-Bromo-2-fluorobenzoic acid

Benzoic acid, 5-bromo-2-fluoro-

CAS: 146328-85-0

Formula: C₇H₄BrFO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 219.0079

Ref: IN-DA001DW0

5-Bromo-2-fluorobenzoic acid

CAS: 146328-85-0

5-Bromo-2-fluorobenzoic acid

Formula: C₇H₄BrFO₂

Purity: 97%

Color and Shape: off white powder

Molecular weight: 219.01g/mol

Ref: 54-PC4107

5-Bromo-2-fluorobenzoic Acid

CAS: 146328-85-0

Formula: C₇H₄BrFO₂

Purity: >97.0%(GC)(T)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 219.01

Ref: 3B-B2974

5-Bromo-2-fluorobenzoic acid

CAS: 146328-85-0

Formula: C₇H₄BrFO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 219.009

Ref: 10-F005477

5-Bromo-2-fluorobenzoic acid

CAS: 146328-85-0

5-Bromo-2-fluorobenzoic acid is a potential drug that can be used to treat diseases such as malaria. It is also used in the synthesis of fluorine compounds, such as fluoroarenes. 5-Bromo-2-fluorobenzoic acid is activated by deprotonation with butyllithium and reacts with chlorine to give the product of 5-bromo-2-chlorobenzoic acid. The reagent chlorotrimethylsilane may also be used for this reaction. Substitution of fluorine for chlorine at the 2 position yields the desired product, 5-bromo-2-(trifluoromethyl)benzoic acid. This compound is a useful intermediate for making other drugs, including those that are important for treating cancer and viral infections.

Formula: C₇H₄BrFO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 219.01 g/mol

Ref: 3D-FB36909