CAS 146328-87-2

5-Cyano-2-fluorobenzoicacid

Description:

5-Cyano-2-fluorobenzoic acid is an aromatic compound characterized by the presence of both a cyano group (-CN) and a fluorine atom attached to a benzoic acid structure. The cyano group contributes to its potential as a versatile building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. The fluorine atom enhances the compound's lipophilicity and can influence its biological activity. This compound typically exhibits solid-state properties at room temperature and is soluble in polar organic solvents. Its acidity is attributed to the carboxylic acid functional group, which can participate in hydrogen bonding and affect its reactivity. The presence of both electron-withdrawing groups (the cyano and fluorine) can significantly influence the electronic properties of the molecule, making it a subject of interest in medicinal chemistry. Safety data should be consulted for handling, as with many chemical substances, due to potential toxicity or environmental impact. Overall, 5-Cyano-2-fluorobenzoic acid is a valuable compound in synthetic organic chemistry.

Formula: C₈H₄FNO₂

Synonyms:

• 5-Cyano-2-fluorobenzoic acid

Benzoic acid, 5-cyano-2-fluoro-

CAS: 146328-87-2

Formula: C₈H₄FNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 165.1213

Ref: IN-DA001DVZ

5-Cyano-2-fluorobenzoic acid

CAS: 146328-87-2

5-Cyano-2-fluorobenzoic acid

Formula: C₈H₄FNO₂

Purity: ≥95%

Color and Shape: white. wooly crystalline powder

Molecular weight: 165.12g/mol

Ref: 54-PC5926

5-Cyano-2-fluorobenzoic acid

CAS: 146328-87-2

5-Cyano-2-fluorobenzoic acid is a macrocyclization agent that is used in the synthesis of 16-membered macrocycles. It is a nucleophilic reagent that reacts with an electrophile to form a 5,5'-bifluoro-2,2'-dioxodibenzofuranone. This reaction can be performed under mild conditions and proceeds via a 1,4-addition mechanism. The product has two stereogenic centers and four stereoisomers that are formed by the relative configuration of these centers. 5-Cyano-2-fluorobenzoic acid also has application in the clinic as an analogue for fluoroquinolones.

Formula: C₈H₄FNO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 165.12 g/mol

Ref: 3D-FC41907

5-Cyano-2-fluorobenzoic acid

CAS: 146328-87-2

Formula: C₈H₄FNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 165.123

Ref: 10-F092334