Description:Fmoc-Ser(BSi)-OH, or 9-fluorenylmethoxycarbonyl-serine (Benzylsilane), is a protected amino acid commonly used in peptide synthesis. The Fmoc group serves as a protective moiety for the amino group, allowing for selective reactions during the synthesis process. This compound features a serine residue, which contains a hydroxyl group that can participate in various chemical reactions, making it versatile in synthetic applications. The presence of the benzylsilane (BSi) group provides additional protection for the hydroxyl functionality, enhancing the stability of the molecule during synthesis. Fmoc-Ser(BSi)-OH is typically used in solid-phase peptide synthesis (SPPS), where its stability under basic conditions is advantageous. The compound is generally soluble in organic solvents, such as dimethylformamide (DMF) and dichloromethane (DCM), but less soluble in water. Its reactivity and stability make it a valuable building block in the development of peptides and other bioactive compounds in medicinal chemistry and biochemistry. Proper handling and storage conditions are essential to maintain its integrity and effectiveness in synthetic applications.
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![L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-](https://static.cymitquimica.com/products/IN/thumb/DA001DXN.jpg)
