CAS 146368-11-8

1-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-2-[(1E,3E,5E)-5-(1-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-3,3-dimethyl-5-sulfo-1,3-dihydro-2H-indol-2-ylidene)penta-1,3-dien-1-yl]-3,3-dimethyl-3H-indolium-5-sulfonate

Description:

The chemical substance known as 1-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-2-[(1E,3E,5E)-5-(1-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-3,3-dimethyl-5-sulfo-1,3-dihydro-2H-indol-2-ylidene)penta-1,3-dien-1-yl]-3,3-dimethyl-3H-indolium-5-sulfonate, with CAS number 146368-11-8, is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as sulfonate, indole, and pyrrolidine moieties. This compound exhibits properties typical of indole derivatives, including potential biological activity, which may be attributed to its ability to interact with various biological targets. The presence of sulfonate groups suggests increased solubility in aqueous environments, enhancing its potential applications in biochemical contexts. Additionally, the dioxopyrrolidine units may contribute to its stability and reactivity. Overall, this substance is likely to be of interest in medicinal chemistry and drug development, particularly for its potential therapeutic applications.

Formula: C₄₅H₅₂N₄O₁₄S₂

InChI: InChI=1/C45H52N4O14S2/c1-44(2)32-28-30(64(56,57)58)18-20-34(32)46(26-12-6-10-16-42(54)62-48-38(50)22-23-39(48)51)36(44)14-8-5-9-15-37-45(3,4)33-29-31(65(59,60)61)19-21-35(33)47(37)27-13-7-11-17-43(55)63-49-40(52)24-25-41(49)53/h5,8-9,14-15,18-21,28-29H,6-7,10-13,16-17,22-27H2,1-4H3,(H-,56,57,58,59,60,61)

SMILES: CC1(C)c2cc(ccc2N(CCCCCC(=O)ON2C(=O)CCC2=O)C1=CC=CC=CC1=[N+](CCCCCC(=O)ON2C(=O)CCC2=O)c2ccc(cc2C1(C)C)S(=O)(=O)[O-])S(=O)(=O)O

Synonyms:

• Cy5
• Cy 5
• 2-((1E,3E,5Z)-5-(1-(5-Carboxypentyl)-3,3-dimethyl-5-(sulfinooxy)indolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate
• 2-(5-(1-(5-Carboxypentyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate
• Sulfo-Cy5-acid
• Cy5-COOH
• Cy 5 acid

Sulfo-cyanine 5 Carboxylic Acid

CAS: 146368-11-8

Formula: C₃₃H₄₀N₂O₈S₂

Purity: >85.0%(T)(HPLC)

Color and Shape: Blue to Dark blue powder to crystal

Molecular weight: 656.81

Ref: 3B-U0172

3H-Indolium, 2-[5-[1-(5-carboxypentyl)-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-ethyl-3,3-dimethyl-5-sulfo-, inner salt

CAS: 146368-11-8

Formula: C₃₃H₄₀N₂O₈S₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 656.8093

Ref: IN-DA001DY3

CY5

CAS: 146368-11-8

CY5

Purity: ≥95%

Molecular weight: 656.81g/mol

Ref: 54-BUP04032

2-(5-(1-(5-Carboxypentyl)-3,3-Dimethyl-5-Sulfoindolin-2-Ylidene)Penta-1,3-Dien-1-Yl)-1-Ethyl-3,3-Dimethyl-3H-Indol-1-Ium-5-Sulfonate

CAS: 146368-11-8

2-(5-(1-(5-Carboxypentyl)-3,3-Dimethyl-5-Sulfoindolin-2-Ylidene)Penta-1,3-Dien-1-Yl)-1-Ethyl-3,3-Dimethyl-3H-Indol-1-Ium-5-Sulfonate

Purity: 97%

Molecular weight: 656.81g/mol

Ref: 54-OR1023902

CY5

CAS: 146368-11-8

Cy5 (Sulfo-Cyanine5) is a phalloidin dye used to label amino groups in peptides, proteins and oligonucleotides.

Formula: C₃₃H₄₀N₂O₈S₂

Purity: 97.18% - 99.86%

Color and Shape: Solid

Molecular weight: 656.81

Ref: TM-T15025

Cyanine dye 5

CAS: 146368-11-8

Cyanine dye 5 is a disulfide-linked dye that has been used as a fluorescence probe in the detection of reactive oxygen species. It has been shown to be reactive with mouse monoclonal antibodies and has been used as a model system for studying calcium binding and DNA duplexes. Cyanine dye 5 is also capable of detecting human serum, mitochondrial membrane potential, and clinical pathology.

Formula: C₃₃H₄₀N₂O₈S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 656.81 g/mol

Ref: 3D-FC75227

CY5

Controlled Product

CAS: 146368-11-8

Formula: C₃₃H₄₀N₂O₈S₂

Color and Shape: Neat

Molecular weight: 656.809

Ref: TR-C951310

CY5 Triethylamine Salt

Controlled Product

CAS: 146368-11-8

Applications CY5 Triethylamine salt is the salt form of CY5(C951310) which is a photoswitchable cyanine dye. The photoswitching mechanism was investigated using thiol agents and it was concluded that photoconversion into the dark state is pH and thiol dependent and the dark state product is a cyanine-thiol adduct.
References Dempsey, G., et al.: J. Am. Chem. Soc., 131, 18192 (2009);

Formula: C₃₃H₄₀N₂O₈S₂·xC₆H₁₅N

Color and Shape: Neat

Molecular weight: 656.81 + x(101.19)

Ref: TR-C951320

Didesulfo Bisbenzyl Cyanine 5 Monofunctional Hexanoic Acid Dye

Controlled Product

CAS: 146368-11-8

Formula: C₄₁H₄₅N₂O₂

Color and Shape: Neat

Molecular weight: 597.808

Ref: TR-D359730

Cyanine dye 5 triethylamine salt

CAS: 146368-11-8

Cyanine dye 5 triethylamine salt is a fluorescent probe that can be used for the detection of cell nuclei and mitochondria. This compound has been shown to react with mouse monoclonal antibody in a subcutaneous tumor model system. It binds to calcium ions and is activated by reactive oxygen species. Cyanine dye 5 triethylamine salt has been shown to have high specificity in cancer tissues, but not in healthy tissues.

Formula: C₃₃H₄₀N₂O₈S₂•C₆H₁₅N

Purity: Min. 95%

Molecular weight: 758 g/mol

Ref: 3D-FC179941