CAS 146408-78-8

Desmethylrocaglamide

Description:

Desmethylrocaglamide is a naturally occurring compound classified as a flavagline, which is derived from the plant species Aglaia. It is known for its potential biological activities, particularly its role as an inhibitor of protein synthesis. The compound exhibits a complex structure characterized by a fused ring system, which contributes to its pharmacological properties. Desmethylrocaglamide has garnered interest in medicinal chemistry due to its cytotoxic effects against various cancer cell lines, suggesting potential applications in cancer therapy. Additionally, it has been studied for its anti-inflammatory and antiviral properties. The substance is typically analyzed using techniques such as nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry to confirm its structure and purity. As with many bioactive compounds, further research is necessary to fully understand its mechanisms of action, therapeutic potential, and safety profile. Overall, desmethylrocaglamide represents a promising area of study in the field of natural product chemistry and drug development.

Formula: C₂₈H₂₉NO₇

Synonyms:

• 1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N-methyl-3-phenyl-, (1R,2R,3S,3aR,8bS)-
• Desmethylrocaglamide

Desmethylrocaglamide

CAS: 146408-78-8

Desmethylrocaglamide: potential cancer treatment, induces cell differentiation, insecticide.

Formula: C₂₈H₂₉NO₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 491.54

Ref: TM-TN3838

Desmethylrocaglamide

CAS: 146408-78-8

Desmethylrocaglamide is a naturally occurring flavagline compound, which is derived from plants, specifically belonging to the family Aglaia (Meliaceae). This compound functions primarily by inhibiting eukaryotic translation initiation, thereby interfering with protein synthesis. The mechanism involves binding to the translation initiation factor eIF4A, leading to inhibition of the helicase activity essential for mRNA binding and ribosome movement.

Formula: C₂₈H₂₉NO₇

Purity: Min. 95%

Molecular weight: 491.5 g/mol

Ref: 3D-WFA40878