CAS 146422-58-4

5-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine

Description:

5-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine is a chemical compound characterized by its unique structural features, which include a tetrahydropyrimidine ring and an oxadiazole moiety. The presence of the oxadiazole ring contributes to its potential biological activity, as oxadiazoles are often associated with various pharmacological properties. This compound may exhibit properties such as antimicrobial, antifungal, or anticancer activities, although specific biological data would be required to confirm these effects. The tetrahydropyrimidine structure can influence the compound's solubility, stability, and reactivity, making it of interest in medicinal chemistry and drug development. Additionally, the ethyl substituent on the oxadiazole ring may enhance lipophilicity, potentially affecting the compound's absorption and distribution in biological systems. Overall, 5-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine represents a class of compounds that could be explored for their therapeutic potential, pending further research and characterization.

Formula: C₈H₁₂N₄O

Synonyms:

• Cdd-0102

CDD0102

CAS: 146422-58-4

CDD0102 is a potent, selective inhibitor of the voltage-gated sodium channel (VGSC) with IC50 values of 2.4 nM for Nav1.8 and 3.2 nM for Nav1.7. CDD0102 is also a highly potent inhibitor of Nav1.5 with an IC50 value of 0.5 nM, which is more than 100-fold better than that of other sodium channel blockers such as tetrodotoxin, saxitoxin, and batrachotoxinin A.
CDD0102 exhibits high affinity binding to the extracellular domain of the VGSCs and has been shown to inhibit both Nav1.8 and Nav1.7 in whole cells with similar potency, while having no effect on other ion channels tested including those belonging to the voltage-gated potassium channel family or the calcium channel family.END>

Formula: C₈H₁₂N₄O

Purity: Min. 95%

Molecular weight: 180.21 g/mol

Ref: 3D-WFA42258

CDD0102

CAS: 146422-58-4

CDD0102 is a potent agonist of M1 Muscarinic receptor.

Formula: C₈H₁₂N₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 180.21

Ref: TM-T10731