CAS: 146426-40-6 - Alvocidib

Formula: C₂₁H₂₀ClNO₅

InChI: InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1

InChI key: InChIKey=BIIVYFLTOXDAOV-YVEFUNNKSA-N

SMILES: O=C1C=C(OC=2C1=C(O)C=C(O)C2C3CCN(C)CC3O)C=4C=CC=CC4Cl

Synonyms:

• (-)-2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-1-benzopyran-4-one
• 2-(2-Chlorophenyl)-5,7-Dihydroxy-8-[(3S,4R)-3-Hydroxy-1-Methyl-4-Piperidyl]Chromen-4-One
• 2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one
• 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3R,4S)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one
• 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-4-piperidinyl)-, cis-(-)-
• 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-
• Alvocidib
• Dsp 2033
• Flavopirodol
• Hl 275
• Hmr 1275
• L 86-8275
• L 868275
• Flavopiridol

4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-

CAS: 146426-40-6

• Formula: C₂₁H₂₀ClNO₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 401.8402

Flavopiridol

CAS: 146426-40-6

• Color and Shape: Solid
• Molecular weight: 401.84g/mol

Flavopiridol

CAS: 146426-40-6

Flavopiridol (Alvocidib) blocks CDK1/2/4/6 by competing with ATP (IC50 ~40 nM); 7.5x selectivity over CDK7; …

• Formula: C₂₁H₂₀ClNO₅
• Purity: 97.74% - 99.85%
• Color and Shape: Solid
• Molecular weight: 401.84

Alvocidib (Flavopiridol)

CAS: 146426-40-6

• Formula: C₂₁H₂₀ClNO₅
• Molecular weight: 401.84

Flavopiridol

CAS: 146426-40-6

Inhibitor of CKD1, CDK2, and CDK4 serine/threonine kinases

• Formula: C₂₁H₂₀ClNO₅
• Purity: Min. 95%
• Color and Shape: Light (Or Pale) Yellow To Yellow Solid
• Molecular weight: 401.103