CAS: 146464-95-1 - 10-Propargyl-10-deazaaminopterin

Formula: C₂₃H₂₃N₇O₅

InChI: InChI=1S/C23H23N7O5/c1-2-3-14(10-15-11-26-20-18(27-15)19(24)29-23(25)30-20)12-4-6-13(7-5-12)21(33)28-16(22(34)35)8-9-17(31)32/h1,4-7,11,14,16H,3,8-10H2,(H,28,33)(H,31,32)(H,34,35)(H4,24,25,26,29,30)/t14?,16-/m0/s1

InChI key: InChIKey=OGSBUKJUDHAQEA-WMCAAGNKSA-N

SMILES: O=C(O)CCC(NC(=O)C1=CC=C(C=C1)C(CC#C)CC=2N=C3C(=NC2)N=C(N=C3N)N)C(=O)O

Synonyms:

• <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butynyl]benzoyl]-
• Folotyn
• N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid
• N-[4-[1-[(2,4-Diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid
• N-{4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}-L-glutamic acid
• NSC 754230
• Pralatrexate

L-Glutamic acid, N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-

CAS: 146464-95-1

• Formula: C₂₃H₂₃N₇O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 477.4726

Pralatrexate

CAS: 146464-95-1

• Formula: C₂₃H₂₃N₇O₅
• Molecular weight: 477.47

Pralatrexate-13C5-15N

CAS: 146464-95-1

• Formula: C₁₈₁₃C₅H₂₃N₆₁₅NO₅
• Color and Shape: Pale Yellow Solid
• Molecular weight: 483.44

Pralatrexate

CAS: 146464-95-1

• Formula: C₂₃H₂₃N₇O₅
• Molecular weight: 477.48

Pralatrexate

CAS: 146464-95-1

Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for …

• Formula: C₂₃H₂₃N₇O₅
• Purity: 94.32% - 99.59%
• Color and Shape: Solid
• Molecular weight: 477.47

Pralatrexate

CAS: 146464-95-1

Pralatrexate is a drug that belongs to a group of drugs called DNA-damaging agents. It …

• Formula: C₂₃H₂₃N₇O₅
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 477.47 g/mol

Pralatrexate-13C5

CAS: 146464-95-1

Applications Pralatrexate-15C5 is labelled Pralatrexate (P700500) which is an antifolate with high affinity for the …

• Formula: C₁₈C₅H₂₃N₇O₅
• Color and Shape: Neat
• Molecular weight: 492.472

Pralatrexate

CAS: 146464-95-1

• Formula: C₂₃H₂₃N₇O₅
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 477.48