CAS 146474-00-2

N-(2-AMINOETHYL)MALEIMIDE TRIFLUOROACETA

Description:

N-(2-Aminoethyl)maleimide trifluoroacetate, with the CAS number 146474-00-2, is a chemical compound characterized by its maleimide functional group, which is known for its ability to undergo Michael addition reactions, making it useful in bioconjugation and polymer chemistry. The presence of the aminoethyl group enhances its reactivity, allowing for the formation of stable linkages with various biomolecules, such as proteins and peptides. The trifluoroacetate moiety contributes to the compound's solubility and stability in various solvents, while also influencing its reactivity. This compound is typically utilized in the synthesis of conjugates for drug delivery systems and in the development of materials with specific functional properties. Its unique structure allows for selective reactions under mild conditions, making it a valuable tool in organic synthesis and materials science. Safety and handling precautions should be observed due to the potential reactivity of the maleimide group and the toxicity associated with trifluoroacetate derivatives.

Formula: C₈H₉F₃N₂O₄

InChI: InChI=1/C6H8N2O2.C2HF3O2/c7-3-4-8-5(9)1-2-6(8)10;3-2(4,5)1(6)7/h1-2H,3-4,7H2;(H,6,7)

SMILES: C1=CC(=O)N(CCN)C1=O.C(=O)(C(F)(F)F)O

Synonyms:

• N-(2-Aminoethyl)maleimid trifluoroacetate salt
• 2-Maleimidoethyl amine・TFA
• 1-(2-Aminoethyl)-1H-Pyrrole-2,5-dione 2,2,2-Trifluoroacetate
• 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethanaminium trifluoroacetate
• N-(2-Aminoethyl)maleimide trifluoroacetate salt,2-Maleimidoethylamine trifluoroacetate salt
• N-(2-AMinoethyl)MaleiMide trifluroaceta
• 2-MaleiMidoethyl aMine
• N-(2-Aminoethyl)maleimide trifluoroacetate salt ,98%
• N-(2-AMinoethyl)MaleiMide trifluoroacetate
• N-(2-AMinoethyl)MaleiMide trifluoroacetic acid salt
• -1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate
• 1-(2-aminoethyl)-1H-pyrrole-2,5-dione TFA salt
• Maleimidoethylamine trifluoroacetate salt
• 2-
• N-(2-AMinoethyl)MaleiMide trifluoroacetate salt >=95% (HPLC), >=98% (T)
• 1-(2-Aminoethyl)
• N-(2-AMINOETHYL)MALEIMIDE TRIFLUOROACETA

1H-Pyrrole-2,5-dione, 1-(2-aminoethyl)-, 2,2,2-trifluoroacetate (1:1)

CAS: 146474-00-2

Formula: C₈H₉F₃N₂O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 254.1633

Ref: IN-DA001E2B

N-(2-Aminoethyl)maleimide, trifluoroacetate salt

CAS: 146474-00-2

N-(2-Aminoethyl)maleimide, trifluoroacetate salt

Formula: C₆H₉N₂O₂·CF₃CO₂

Purity: ≥95%

Color and Shape: white to off white solid

Molecular weight: 254.16g/mol

Ref: 54-PC8112

Mal-NH2 TFA

CAS: 146474-00-2

Mal-NH2 TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Formula: C₈H₉F₃N₂O₄

Color and Shape: Solid

Molecular weight: 254.16

Ref: TM-T15972

1-(2-Aminoethyl)-1H-pyrrole-2,5-dione Trifluoroacetate

CAS: 146474-00-2

Formula: C₆H₈N₂O₂·C₂HF₃O₂

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 254.17

Ref: 3B-A3663

N-(2-Aminoethyl)maleimide Trifluoroacetic Acid Salt

Controlled Product

CAS: 146474-00-2

Applications A thiol-reactive cross-linking reagent.
References Licha, K., & Perlitz, C.: PCT Int. Appl. (2004), WO 2004065491 A1; Gutierrez, C. B., et al.: Analytical Chemistry (Washington, DC, US), 90, 7600 (2018)

Formula: C₆H₈N₂O₂·C₂HF₃O₂

Color and Shape: Neat

Molecular weight: 254.16

Ref: TR-A609050

1-(2-Aminoethyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate

CAS: 146474-00-2

Formula: C₈H₉F₃N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 254.165

Ref: 10-F238845

N-(2-Aminoethyl)maleimide trifluoroacetic acid

CAS: 146474-00-2

N-(2-Aminoethyl)maleimide trifluoroacetate is an amino acid derivative that is used as a chemical probe. The maleimido group in this compound reacts with the nucleophilic groups on proteins to form stable covalent bonds, which can be observed by positron emission tomography (PET) imaging. This chemical probe has been used to image glucagon-like peptide (GLP)-1 receptors in the pancreas and insulinomas, as well as reactive regions of the brain. The uptake of N-(2-Aminoethyl)maleimide trifluoroacetic acid can be enhanced through functionalizing the molecule with reactive groups such as maleimido or trifluoroacetate.

Formula: C₈H₉F₃N₂O₄

Purity: Min. 95.0 Area-%

Molecular weight: 254.16 g/mol

Ref: 3D-FA17748