Follicle-stimulating hormone (FSH) is a glycoprotein hormone produced by the anterior pituitary gland, playing a crucial role in reproductive processes. It is essential for the regulation of the menstrual cycle in females and the production of sperm in males. FSH is composed of two subunits, alpha and beta, which are linked by non-covalent interactions; the beta subunit is unique to FSH and determines its biological activity. The hormone stimulates the growth and maturation of ovarian follicles in females and promotes spermatogenesis in males by acting on specific receptors in the gonads. FSH is typically administered in clinical settings for fertility treatments and is characterized by its relatively large molecular weight due to its glycosylation. The CAS number 146479-72-3 identifies a specific formulation or preparation of FSH, which may vary in its purity and biological activity. Overall, FSH is vital for normal reproductive function and is a key target in the treatment of various fertility disorders.

Follitropin beta is a human FSH preparation of rDNA origin, which differs chemically from 
natural FSH and follitropin alfa only by slight variances in the composition of the carbohydrate 
side chains. In fact, the primary and tertiary structures of both follitropins alfa and beta are 
indistinguishable from those of human FSH of natural origin. Furthermore, bioassays and 
physiochemical studies indicate that follitropins alfa and beta are indistinguishable from each 
other. Therefore, it is not surprising that follitropin beta is approved for the same medical uses 
as follitropin alpha.

Follicle-stimulating hormone

146479-72-3: Follicle-stimulating hormone (FSH) is a glycoprotein hormone produced by the anterior pituitary gland, playing a crucial role in reproductive processes. It is essential for the regulation of the menstrual cycle in females and the production of sperm in males. FSH is composed of two subunits, alpha and beta, which are linked by non-covalent interactions; the beta subunit is unique to FSH and determines its biological activity. The hormone stimulates the growth and maturation of ovarian follicles in females and promotes spermatogenesis in males by acting on specific receptors in the gonads. FSH is typically administered in clinical settings for fertility treatments and is characterized by its relatively large molecular weight due to its glycosylation. The CAS number 146479-72-3 identifies a specific formulation or preparation of FSH, which may vary in its purity and biological activity. Overall, FSH is vital for normal reproductive function and is a key target in the treatment of various fertility disorders.

CAS 146479-72-3

Follicle-stimulating hormone

FOLLITROPIN CRS

Ref: 41-Y0001629