CAS 14653-77-1

Ethanethiol, 2-[(3-aminopropyl)amino]-, hydrochloride (1:2)

Description:

Ethanethiol, 2-[(3-aminopropyl)amino]-, hydrochloride (1:2), with CAS number 14653-77-1, is a chemical compound characterized by its amine and thiol functional groups. This substance typically appears as a white to off-white crystalline solid and is soluble in water due to the presence of the hydrochloride salt form, which enhances its solubility compared to the free base. The compound features a thiol group (-SH) that imparts distinct odor characteristics, often described as similar to rotten eggs, and can be reactive in various chemical environments. Its amine component suggests potential basicity and the ability to form hydrogen bonds, which can influence its reactivity and interactions with other molecules. This compound may be utilized in various applications, including pharmaceuticals and biochemical research, particularly in studies involving amino acids or as a building block in organic synthesis. Safety precautions should be observed when handling this substance due to its potential toxicity and irritant properties.

Formula: C₅H₁₄N₂S·2ClH

InChI: InChI=1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H

InChI key: InChIKey=XDRLRDHLCIFZIW-UHFFFAOYSA-N

SMILES: C(NCCS)CCN.Cl

Synonyms:

• Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrochloride
• Ethanethiol, 2-[(3-aminopropyl)amino]-, hydrochloride (1:2)
• Wr 1065
• ethanethiol, 2-[(3-aminopropyl)amino]-
• 2-((3-Aminopropyl)Amino)Ethanethiol Dihydrochloride
• 2-((3-Aminopropyl)amino)ethyl hydrosulfide
• WR-1065 hydrochloride

Amifostine Thiol (Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrochloride)

CAS: 14653-77-1

Organo-sulfur compounds, nesoi

Formula: C₅H₁₆N₂SCl₂

Color and Shape: White Powder

Molecular weight: 206.04113

Ref: 45-1019428

Ethanethiol, 2-[(3-aminopropyl)amino]-, hydrochloride (1:2)

CAS: 14653-77-1

Formula: C₅H₁₆Cl₂N₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 207.1649

Ref: IN-DA001E3U

2-((3-Aminopropyl)Amino)Ethanethiol Dihydrochloride

CAS: 14653-77-1

2-((3-Aminopropyl)Amino)Ethanethiol Dihydrochloride

Purity: 95%

Molecular weight: 207.16g/mol

Ref: 54-OR1009614

Amifostine thiol dihydrochloride

CAS: 14653-77-1

Amifostine thiol dihydrochloride

Purity: ≥95%

Molecular weight: 207.165g/mol

Ref: 54-BUP06721

Amifostine Thiol Ditrifluoroacetate

CAS: 14653-77-1, 31098-42-7

Formula: C₅H₁₄N₂S·2C₂HF₃O₂

Molecular weight: 134.24 2*114.02

Ref: 4Z-A-256013

Amifostine thiol dihydrochloride

CAS: 14653-77-1

Amifostine (WR 1065) activates p53 via JNK and shields tissues from cancer drug toxicity.

Formula: C₅H₁₆Cl₂N₂S

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 207.165

Ref: TM-TQ0133

Amifostine Thiol Dihydrochloride >90%

CAS: 14653-77-1

Stability Hygroscopic
Applications Amifostine Thiol is a metabolite of Amifostine (A576810) which provides normal cells with selective protection against the toxic effects of cancer chemotherapy and radiation treatment.
References Satge, J., et al.: Eur. J. Med. Chem., 24, 48 (1989); Geary, R.S., et al.: Biopharm. Drug Dispos., 12, 261 (1991); Brown, D.Q., et al. Pharmacol. Ther., 39, 159 (1988); Capizzi, R.L., et al.: Cancer, 72, 3495 (1993); Treskes, M., et al.: Cancer Chemother. Pharmacol., 33, 93 (1993)

Formula: C₅H₁₄N₂S·2ClH

Purity: >90%

Color and Shape: Neat

Molecular weight: 207.16

Ref: TR-A576820

2-((3-AMINOPROPYL)AMINO)ETHANETHIOL 2HCL

CAS: 14653-77-1

Formula: C₅H₁₆Cl₂N₂S

Purity: 98%

Molecular weight: 207.16

Ref: 10-F530869

Amifostine Thiol Dihydrochloride-d4

Controlled Product

CAS: 14653-77-1

Formula: C₅H₁₂D₄Cl₂N₂S

Color and Shape: Neat

Molecular weight: 138.268

Ref: TR-A576822