Description:Tyrphostin AG 1296 is a selective inhibitor of the protein tyrosine kinase activity, specifically targeting the platelet-derived growth factor (PDGF) receptor. This compound is known for its role in research related to cell signaling pathways, particularly in the context of cancer and cellular proliferation. It exhibits characteristics typical of small organic molecules, including a relatively low molecular weight and the ability to penetrate cell membranes, which facilitates its action within cells. Tyrphostin AG 1296 has been utilized in various studies to investigate the effects of tyrosine kinase inhibition on cellular processes such as growth, differentiation, and migration. Its mechanism of action involves blocking the phosphorylation of tyrosine residues, which is crucial for the activation of signaling cascades that promote cell division and survival. As a research tool, it has contributed to a better understanding of the role of tyrosine kinases in disease mechanisms, particularly in oncology and developmental biology. However, like many chemical inhibitors, its use is primarily confined to laboratory settings and requires careful handling due to potential biological activity.
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