CAS 146555-78-4

Pyrrolo[4,3,2-de]quinolin-8(1H)-one,7-amino-3,4-dihydro-1-methyl-

CAS: 146555-78-4

Formula: C₁₁H₁₁N₃O

Molecular weight: 201.2245

Ref: IN-DA001E51

Makaluvamine A

CAS: 146555-78-4

Makaluvamine A is a marine-derived alkaloid compound, which is sourced from marine sponges, specifically of the genus Zyzzya. This class of compounds is notable for its cytotoxic properties against various cancer cell lines. The mode of action of Makaluvamine A involves intercalating with DNA, thereby disrupting the DNA replication process. This intercalation primarily hinders the activity of DNA topoisomerases, enzymes critical for DNA unwinding during replication and transcription.

Formula: C₁₁H₁₁N₃O

Purity: Min. 95%

Molecular weight: 201.22 g/mol

Ref: 3D-WFA55578

Makaluvamine A

CAS: 146555-78-4

Makaluvamine A comes from the fruiting bodies of Didymium bahiense that act as active anti-cancer agents and DNA topo II inhibitors.

Formula: C₁₁H₁₁N₃O

Color and Shape: Solid

Molecular weight: 201.22

Ref: TM-T70592