CAS 146613-90-3

saprisartan potassium

Description:

Saprisartan potassium is a pharmaceutical compound primarily used as an antihypertensive agent. It belongs to the class of angiotensin II receptor antagonists, which function by blocking the action of angiotensin II, a peptide that causes blood vessels to constrict, thereby lowering blood pressure. The compound is characterized by its potassium salt form, which enhances its solubility and bioavailability. Saprisartan potassium is typically administered orally and is known for its efficacy in managing hypertension and potentially providing renal protective effects. Its chemical structure includes a biphenyl moiety, contributing to its receptor-binding properties. The substance is generally well-tolerated, with a side effect profile similar to other drugs in its class, including dizziness and fatigue. As with any medication, it is essential to consider contraindications and interactions with other drugs. Overall, saprisartan potassium represents a valuable option in the therapeutic management of high blood pressure, contributing to cardiovascular health.

Formula: C₂₅H₂₁BrF₃KN₄O₄S

InChI: InChI=1/C25H21BrF3N4O4S.K/c1-2-19-31-21(14-8-9-14)22(24(30)34)33(19)12-13-7-10-18-16(11-13)20(26)23(37-18)15-5-3-4-6-17(15)32-38(35,36)25(27,28)29;/h3-7,10-11,14H,2,8-9,12H2,1H3,(H2,30,34);/q-1;+1

SMILES: CCc1nc(C2CC2)c(C(=N)O)n1Cc1ccc2c(c1)c(c(c1ccccc1[N-]S(=O)(=O)C(F)(F)F)o2)Br.K

Synonyms:

• Saprisartan potassium [USAN]
• 1-((3-Bromo-2-(o-(1,1,1-(trifluoromethanesulfonamido)phenyl)-5-benzofuranyl)methyl)-4-cyclopropyl-2-ethylimidazole-5-carboxamide, monopotassium salt
• 1H-Imidazole-5-carboxamide, 1-((3-bromo-2-(2-(((trifluoromethyl)sulfonyl)amino)phenyl-5-benzofuranyl)methyl)-4-cyclopropyl-2-ethyl-, monopotassium salt
• Gr 138950C
• potassium (2-{3-bromo-5-[(5-carbamoyl-4-cyclopropyl-2-ethyl-1H-imidazol-1-yl)methyl]-1-benzofuran-2-yl}phenyl)[(trifluoromethyl)sulfonyl]azanide
• Saprisartan potassium

Saprisartan potassium

CAS: 146613-90-3

Saprisartan potassium is an Angiotensin II Type 1 receptor antagonist and antihypertensive agent.

Formula: C₂₅H₂₁BrF₃KN₄O₄S

Color and Shape: Solid

Molecular weight: 649.52

Ref: TM-T70589