CAS 14663-46-8

3-Amino-4(3H)-quinazolinone

Description:

3-Amino-4(3H)-quinazolinone, with the CAS number 14663-46-8, is an organic compound characterized by its quinazolinone structure, which features a fused bicyclic ring system containing both a benzene and a pyrimidine ring. This compound typically exhibits a white to off-white crystalline appearance and is known for its solubility in polar solvents such as water and alcohols. The presence of an amino group at the 3-position contributes to its basicity and potential reactivity, making it a candidate for various chemical reactions, including substitution and coupling reactions. 3-Amino-4(3H)-quinazolinone has garnered interest in medicinal chemistry due to its potential biological activities, including antimicrobial and anticancer properties. Its derivatives are often explored for therapeutic applications, highlighting the importance of this compound in pharmaceutical research. Additionally, it may serve as an intermediate in the synthesis of more complex organic molecules, showcasing its versatility in organic synthesis.

Formula: C₈H₇N₃O

InChI: InChI=1S/C8H7N3O/c9-11-5-10-7-4-2-1-3-6(7)8(11)12/h1-5H,9H2

InChI key: InChIKey=XZRJWCFKYOZVIH-UHFFFAOYSA-N

SMILES: O=C1C=2C(N=CN1N)=CC=CC2

Synonyms:

• 2-Amino-2H-quinazolin-1-one
• 3-Amino-3,4-dihydroquinazolin-4-one
• 3-Amino-3H-quinazolin-4-one
• 3-Amino-4(3H)-Quinazolinon
• 3-Amino-4(3H)-quinazolinone
• 3-Amino-4-quinazolone
• 3-Aminoquinazolin-4-one
• 3-aminoquinazolin-4(3H)-one
• 4(3H)-Quinazolinone, 3-amino-
• NSC 113673
• NSC 59161

3-Amino-3,4-dihydroquinazolin-4-one

CAS: 14663-46-8

3-Amino-3,4-dihydroquinazolin-4-one

Purity: 95%

Molecular weight: 161.16g/mol

Ref: 54-OR1006262

3-Amino-3,4-dihydroquinazolin-4-one

CAS: 14663-46-8

Purity: 95%

Molecular weight: 161.1640015

Ref: 10-F644924

3-Amino-4(3H)-quinazolinone

CAS: 14663-46-8

3-Amino-4(3H)-quinazolinone is a nucleophilic compound that can react with methyl anthranilate, an anthranilic acid derivative. When reacted with aziridine, 3-amino-4(3H) quinazolinone forms a hydroxyl group. This compound is cytotoxic to human liver cells in vitro and exhibits significant cytotoxicity against cancer cells. It has been shown to inhibit the growth of epidermal growth factor (EGF) in vitro and can be used as a tumor promoter. 3-Amino-4(3H)-quinazolinone also reacts with amines such as amino acids, amides, and ammonia to form aziridinium ions. Aziridinium ions are nitrogen nucleophiles that can react with other molecules to form new compounds or break down existing ones.

Formula: C₈H₇N₃O

Purity: Min. 95%

Molecular weight: 161.16 g/mol

Ref: 3D-PAA66346