CAS 146645-63-8

1-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan

Description:

1-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan is a chemical compound that belongs to the class of amino acids, specifically a derivative of L-tryptophan. This compound features a tryptophan backbone, which is an essential amino acid known for its role in protein synthesis and as a precursor to serotonin. The presence of the 1,1-dimethylethoxycarbonyl group enhances its stability and solubility, making it useful in various biochemical applications. The compound is typically characterized by its molecular structure, which includes a tryptophan side chain and a protective group that can be removed in synthetic processes. It is often utilized in peptide synthesis and drug development due to its ability to participate in various chemical reactions while maintaining the integrity of the tryptophan moiety. Additionally, its unique functional groups may impart specific reactivity and interaction properties, making it a valuable compound in medicinal chemistry and biochemistry.

Formula: C₁₆H₂₀N₂O₄

InChI: InChI=1/C16H20N2O4/c1-16(2,3)22-15(21)18-9-10(8-12(17)14(19)20)11-6-4-5-7-13(11)18/h4-7,9,12H,8,17H2,1-3H3,(H,19,20)/t12-/m0/s1

InChI key: InChIKey=DYWUPCCKOVTCFZ-LBPRGKRZSA-N

SMILES: C(OC(C)(C)C)(=O)N1C=2C(C(C[C@@H](C(O)=O)N)=C1)=CC=CC2

Synonyms:

• 1-(tert-butoxycarbonyl)-L-tryptophan
• 1-Boc-<span class="text-smallcaps">L</span>-tryptophan
• 1-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tryptophan
• <span class="text-smallcaps">L</span>-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-
• N-In-Boc-L-Tryptophan
• N-Indole-T-Butoxycarbonyl-L-Tryptophan
• 1-Boc-L-tryptophan
• 1-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan
• L-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-
• H-Trp(Boc)-OH
• (S)-2-amino-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)propanoic acid
• H-TRP(BOC)-OH;H-TRP(BOC)-OH;N-IN-BOC-L-TRYPTOPHAN;N-INDOLE-T-BUTOXYCARBONYL-L-TRYPTOPHAN
• (2S)-2-amino-3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propanoic acid
• (2S)-2-amino-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
• H-TRP(BOC)-OH USP/EP/BP
• Nin-Boc-L-tryptophan≥ 99% (HPLC)
• 1-Boc-D-tryptophan, 95%
• N-Indole-T-Boc-L-tryptophan
• (2S)-2-amino-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoicaci
• L-Trp(Boc)-OH

H-Trp(Boc)-OH

CAS: 146645-63-8

Bachem ID: 4017673.

Formula: C₁₆H₂₀N₂O₄

Purity: ≥ 99%

Color and Shape: White

Molecular weight: 304.35

Ref: 01-4017673

L-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-

CAS: 146645-63-8

Formula: C₁₆H₂₀N₂O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 304.3410

Ref: IN-DA00HXIC

H-Trp(Boc)-OH

CAS: 146645-63-8

H-Trp(Boc)-OH

Purity: 98%

Molecular weight: 304.34g/mol

Ref: 54-OR1013535

H-Trp(Boc)-OH

CAS: 146645-63-8

M06070 - H-Trp(Boc)-OH

Formula: C₁₆H₂₀N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 304.346

Ref: 10-M06070

H-Trp(Boc)-OH

CAS: 146645-63-8

H-Trp(Boc)-OH is an antiproliferative molecule that has been synthesized as a template molecule for the synthesis of analogs. It has been found to have cytotoxic and antiproliferative effects on cancer cells in culture. H-Trp(Boc)-OH is an enantiomer of the natural amino acid, tryptophan, and was postulated to be able to inhibit tumor growth by alkylation. This compound can also be synthesized using a solid-phase synthesis. H-Trp(Boc)-OH is an analog of desotamide, which inhibits the enzyme DNA polymerase α that catalyzes the conversion of deoxyribonucleoside triphosphates into DNA. The chloride ion in this compound may be responsible for its cytotoxic effects on cancer cells in culture.

Formula: C₁₆H₂₀N₂O₄

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 304.34 g/mol

Ref: 3D-FN48185