Description:(RS)-MCPG, or (RS)-2-Methyl-2-(3-carboxyphenyl)glycine, is a chemical compound that functions primarily as a selective antagonist of the metabotropic glutamate receptor subtype 2 (mGluR2). It is often utilized in neuropharmacological research to study the role of glutamate in various neurological conditions. The compound is characterized by its ability to modulate neurotransmission, making it a valuable tool in understanding synaptic plasticity and potential therapeutic targets for disorders such as anxiety, depression, and schizophrenia. (RS)-MCPG is typically presented as a white to off-white solid and is soluble in water and organic solvents, which facilitates its use in biological assays. Its molecular structure includes a carboxylic acid group, contributing to its acidic properties, and a phenyl ring that enhances its interaction with biological targets. Safety data indicates that, like many chemical substances, it should be handled with care, following appropriate safety protocols in laboratory settings.
(RS)-3-Methoxy-4-(2-methylpropyl)phenylglycine (MCPG), also known as (RS)-3,4-dimethoxyphenylglycine, is a serotonin agonist with high affinity for the …
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