2-(2-Hydroxybutyl)-N'1,N'3-diphenylmalonohydrazide, with the CAS number 14668-59-8, is a chemical compound that belongs to the class of hydrazides. This substance features a malonohydrazide core, which is characterized by the presence of two phenyl groups attached to the nitrogen atoms, enhancing its stability and reactivity. The hydroxybutyl substituent contributes to its solubility and potential interactions in various chemical environments. Typically, compounds of this nature exhibit properties such as moderate to high melting points, and they may be soluble in organic solvents while being less soluble in water. The presence of functional groups like hydroxyl and hydrazide can impart biological activity, making such compounds of interest in medicinal chemistry and materials science. Additionally, the structural features suggest potential applications in fields such as polymer chemistry, where they may serve as intermediates or additives. Overall, the characteristics of this compound make it a subject of interest for further research and application in various chemical processes.

2-(2-hydroxybutyl)-N'~1~,N'~3~-diphenylmalonohydrazide

14668-59-8: 2-(2-Hydroxybutyl)-N'1,N'3-diphenylmalonohydrazide, with the CAS number 14668-59-8, is a chemical compound that belongs to the class of hydrazides. This substance features a malonohydrazide core, which is characterized by the presence of two phenyl groups attached to the nitrogen atoms, enhancing its stability and reactivity. The hydroxybutyl substituent contributes to its solubility and potential interactions in various chemical environments. Typically, compounds of this nature exhibit properties such as moderate to high melting points, and they may be soluble in organic solvents while being less soluble in water. The presence of functional groups like hydroxyl and hydrazide can impart biological activity, making such compounds of interest in medicinal chemistry and materials science. Additionally, the structural features suggest potential applications in fields such as polymer chemistry, where they may serve as intermediates or additives. Overall, the characteristics of this compound make it a subject of interest for further research and application in various chemical processes.

<p>SLC7A11-IN-2 (Compound 1) is an inhibitor of SLC7A11/xCT. It disrupts the oxidative balance in HeLa cells by decreasing intracellular glutathione levels and increasing oxidative stress, thereby inducing cell death with an IC50 of 10.23 μM. Molecular dynamics simulations have demonstrated that SLC7A11-IN-2 exhibits a stronger binding affinity to SLC7A11 compared to Erastin. This compound is useful for research in the field of cervical cancer.</p>

CAS 14668-59-8

2-(2-hydroxybutyl)-N'~1~,N'~3~-diphenylmalonohydrazide

SLC7A11-IN-2

Ref: TM-T200659