CAS 1467059-66-0

(S)-4,6-Difluoro-5-(4-(tetrahydro-2H-pyran-2-yl)phenyl)-1H-indole-3-carboxylic acid

CAS: 1467059-66-0

(S)-4,6-Difluoro-5-(4-(tetrahydro-2H-pyran-2-yl)phenyl)-1H-indole-3-carboxylic acid

Purity: 98%

Molecular weight: 357.36g/mol

Ref: 54-PC1007734

PF-06679142

CAS: 1467059-66-0

PF-06679142 is a research tool that is used for the study of receptor and ion channel interactions. It is an activator of the nicotinic acetylcholine receptor (nAChR) and has been shown to block ligand binding to the nAChR. PF-06679142 also binds to cell-surface receptors, such as the human epidermal growth factor receptor 2 (HER2), and may be useful in targeting cancer cells. This compound has been shown to inhibit protein synthesis by inhibiting peptide bond formation through competitive inhibition of aminopeptidase N. PF-06679142 belongs to a group of peptides called "N"-substituted glycine analogues, which are used as pharmacological tools for studying protein interactions.

Formula: C₂₀H₁₇F₂NO₃

Purity: Min. 95%

Molecular weight: 357.3 g/mol

Ref: 3D-SIC05966

PF-06679142

CAS: 1467059-66-0

PF-06679142 is an effective AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption.

Formula: C₂₀H₁₇F₂NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 357.35

Ref: TM-T24622