CAS 146713-21-5

Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-6-S-(2-cyanoethyl)-2′-deoxy-6-thio-N-(trifluoroacetyl)-

Description:

Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-6-S-(2-cyanoethyl)-2′-deoxy-6-thio-N-(trifluoroacetyl)-, identified by CAS number 146713-21-5, is a modified nucleoside derivative of guanosine. This compound features a guanine base linked to a ribose sugar, which is further modified at the 5' position with a bis(4-methoxyphenyl)phenylmethyl group, enhancing its lipophilicity and potentially influencing its biological activity. The presence of a 6-thio group and a trifluoroacetyl moiety suggests that it may exhibit unique reactivity and stability characteristics compared to unmodified nucleosides. The cyanoethyl group at the 6-position may also play a role in its chemical behavior and interactions. Such modifications can affect the compound's solubility, permeability, and affinity for biological targets, making it of interest in medicinal chemistry and drug development. Overall, this compound exemplifies the structural complexity and functional diversity found in nucleoside analogs, which are often explored for therapeutic applications, particularly in antiviral and anticancer research.

Formula: C₃₆H₃₃F₃N₆O₆S

Synonyms:

• Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-6-S-(2-cyanoethyl)-2′-deoxy-6-thio-N-(trifluoroacetyl)-

5'-O-DMT-S6-cyanoethyl-N2-TFA-2'-deoxyguanosine

CAS: 146713-21-5

Base labile TFA protected deoxyguanosine

Formula: C₃₆H₃₃F₃N₆O₆S

Molecular weight: 734.75 g/mol

Ref: 3D-ND02363