CAS 146724-94-9

Diethylamine NONOate

Description:

Diethylamine NONOate, with the CAS number 146724-94-9, is a chemical compound that belongs to the class of non-steroidal nitric oxide donors. It is characterized by its ability to release nitric oxide (NO) upon decomposition, which plays a crucial role in various biological processes, including vasodilation and neurotransmission. The compound typically appears as a colorless to pale yellow liquid and is soluble in water and organic solvents. Its structure features a diethylamine moiety, which contributes to its basicity and potential interactions with biological systems. Diethylamine NONOate is often used in research settings to study the effects of nitric oxide in cellular signaling and its implications in cardiovascular health, neurobiology, and other physiological processes. Safety data indicates that, like many nitrogen-containing compounds, it should be handled with care due to potential toxicity and reactivity. Proper storage and handling protocols are essential to ensure safety in laboratory environments.

Formula: C₄H₁₃N₅O₂

InChI: InChI=1S/C4H13N5O2/c5-1-3-8(4-2-6)9(11)7-10/h11H,1-6H2

InChI key: InChIKey=HMRRJTFDJAVRMR-UHFFFAOYSA-N

SMILES: N(N(N=O)O)(CCN)CCN

Synonyms:

• 1,1-Bis(2-Aminoethyl)-2-Hydroxy-3-Oxotriazane
• 1-Hydroxy-2-Oxo-3,3-Bis(3-Aminoethyl)-1-Triazene
• 2,2'-(2-Hydroxy-3-Oxotriazane-1,1-Diyl)Diethanaminium
• 2,2'-(Hydroxynitrosohydrazino)Bis-Ethamine
• 2,2'-(Hydroxynitrosohydrazino)Bis-Ethanamine
• 2,2′-(2-Hydroxy-2-nitrosohydrazinylidene)bis[ethanamine]
• 3,3-Bis(Aminoethyl)-1-Hydroxy-2-Oxo-1-Triazene
• Deta Nonoate
• Deta/No
• Diethylamine NONOate
• Diethylamine diazeniumdiolate
• Diethylenetriamine Nonoate
• Ethanamine, 2,2′-(2-hydroxy-2-nitrosohydrazinylidene)bis-
• Ethanamine, 2,2′-(hydroxynitrosohydrazono)bis-

Ethanamine, 2,2'-(hydroxynitrosohydrazono)bis-

CAS: 146724-94-9

Formula: C₄H₁₃N₅O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 163.1783

Ref: IN-DA01DP5O

DETA NONOate

CAS: 146724-94-9

DETA NONOate

Purity: ≥98%

Molecular weight: 163.18g/mol

Ref: 54-BUP21373

DETA NONOate

CAS: 146724-94-9

DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor with vasodilatory and antidepressant activity that accelerates healing of MRSA infected wounds.

Formula: C₄H₁₃N₅O₂

Purity: 98.00% - 99.60%

Color and Shape: Solid

Molecular weight: 163.18

Ref: TM-T36033

Detanonoate

CAS: 146724-94-9

Detanonoate is a cyclase inhibitor that can induce apoptosis and inhibit the production of pro-inflammatory cytokines. Detanonoate has been shown to be minimally toxic in cell culture studies and to have a minimal effect on enzyme activity. Detanonoate also has significant cytotoxicity against tumor cells, with minimal toxicity against normal cells. It also exerts an anti-inflammatory effect through its inhibition of toll-like receptor 4, which is involved in the inflammatory response. Detanonoate has been shown to decrease tumor growth by inhibiting matrix metalloproteinase-9 (MMP-9) activity, which may be due to its ability to inhibit mitochondrial membrane potential. Detanonoate is used for the treatment of bowel disease.

Formula: C₄H₁₃N₅O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 163.18 g/mol

Ref: 3D-FD16348