CAS 14679-73-3

Todralazine

Description:

Todralazine is a chemical compound primarily recognized for its use as an antihypertensive agent. It belongs to the class of medications known as vasodilators, which work by relaxing blood vessels to lower blood pressure. The molecular structure of Todralazine features a hydrazine moiety, which is significant for its pharmacological activity. It is typically administered in oral form and is known to have a moderate onset of action. The compound exhibits a relatively low solubility in water, which can influence its bioavailability and absorption in the body. Todralazine's mechanism of action involves the inhibition of certain neurotransmitters and the modulation of vascular smooth muscle tone, contributing to its effectiveness in managing hypertension. As with many medications, potential side effects may include dizziness, headache, or gastrointestinal disturbances. It is essential for patients to consult healthcare professionals for appropriate dosing and to discuss any contraindications or interactions with other medications. Overall, Todralazine represents a valuable option in the therapeutic management of high blood pressure.

Formula: C₁₁H₁₂N₄O₂

InChI: InChI=1S/C11H12N4O2/c1-2-17-11(16)15-14-10-9-6-4-3-5-8(9)7-12-13-10/h3-7H,2H2,1H3,(H,13,14)(H,15,16)

InChI key: InChIKey=WGZDBVOTUVNQFP-UHFFFAOYSA-N

SMILES: N(NC(OCC)=O)C=1C2=C(C=NN1)C=CC=C2

Synonyms:

• 2-(1-Phthalazinyl)Hydrazinecarboxylic acid ethyl ester
• 3-(1-Phthalazinyl)carbazic acid ethyl ester
• Brn 0233300
• Bt 621
• Carbazic acid, 3-(1-phthalazinyl)-, ethyl ester
• Carboethoxyphthalazinohydrazine
• Ethyl 2-(Phthalazin-1-Yl)Hydrazinecarboxylate
• Ethyl 2-(Phthalazin-1-Yl)Hydrazinecarboxylate Hydrochloride (1:1)
• Ethyl 3-(1-phthalazinyl)carbazate
• Hydrazinecarboxylic acid, 2-(1-phthalazinyl)-, ethyl ester
• Hydrazinecarboxylic acid, 2-(1-phthalazinyl)-, ethyl ester (9CI)
• N-Carboethoxy-N'-phthalazino-hydrazine
• N¹-Carbethoxy-N²-phthalazinehydrazine
• Todralacina
• Todralacina [Spanish]
• Todralazina
• Todralazina [INN-Spanish]
• Todralazine [INN:BAN]
• Todralazinum
• Todralazinum [INN-Latin]
• Unii-Wen3K83Ykd
• N1-Carbethoxy-N2-phthalazinehydrazine

Todralazine

CAS: 14679-73-3

Todralazine is a potassium dichromate salt that is used for the treatment of inflammatory bowel disease. Todralazine is an anti-inflammatory drug and has been shown to reduce the production of cytokines, such as IL-1β and IL-6, in human serum. Todralazine also inhibits genotoxic activity by suppressing reactive oxygen species (ROS) production. Todralazine may be able to stabilize chemical reactions, which can be useful in biocompatible polymers. It has been shown to be effective in congestive heart failure; however, it can cause bowel disease if taken long term.

Formula: C₁₁H₁₂N₄O₂

Purity: Min. 95%

Molecular weight: 232.24 g/mol

Ref: 3D-PAA67973

Todralazine

CAS: 14679-73-3

Todralazine is an anti-hypertensive agent and acts as a β2AR blocker. It also has an antioxidant and free radical scavenging activity.

Formula: C₁₁H₁₂N₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 232.24

Ref: TM-T17112