CAS 14685-79-1

2-CHLORO-2-DEOXY-D-GLUCOSE

Description:

2-Chloro-2-deoxy-D-glucose (CAS 14685-79-1) is a synthetic analog of glucose, where the hydroxyl group at the second carbon is replaced by a chlorine atom. This modification imparts unique characteristics to the compound, making it a useful tool in biochemical research, particularly in studies involving glucose metabolism and transport. It is a white to off-white crystalline powder that is soluble in water, reflecting its polar nature due to the presence of hydroxyl groups on other carbons. The compound is often utilized in studies of cellular uptake mechanisms, as it can inhibit glucose transporters, thereby affecting cellular metabolism. Additionally, 2-chloro-2-deoxy-D-glucose can serve as a radiolabeled tracer in positron emission tomography (PET) imaging, allowing researchers to visualize glucose metabolism in vivo. Its structural similarity to glucose enables it to compete with glucose for uptake by cells, making it a valuable compound in metabolic studies and potential therapeutic applications in conditions such as cancer, where altered glucose metabolism is a hallmark.

Formula: C₆H₁₁ClO₅

InChI: InChI=1/C6H11ClO5/c7-3(1-8)5(11)6(12)4(10)2-9/h1,3-6,9-12H,2H2/t3-,4+,5+,6+/m0/s1

Synonyms:

• 2-Deoxy-2-Chloro-D-Glucose
• 2-Chloro-Dg
• 2-Cldg
• 2-Chloro-2-Deoxy-D-Glucose Analog Of 2-F Luoro-2-
• 2-Cidg
• 2-Chloro-2-Deoxyglucose
• ClDG

Fludeoxyglucose Related Compound B (2-chloro-2-deoxy-D-glucose)

CAS: 14685-79-1

Heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₆H₁₁ClO₅

Color and Shape: White Off-White Powder

Molecular weight: 198.0295

Ref: 45-1272929

D-Glucose, 2-chloro-2-deoxy-

CAS: 14685-79-1

Formula: C₆H₁₁ClO₅

Purity: 90%

Color and Shape: Solid

Molecular weight: 198.6015

Ref: IN-DA001EDZ

2-Chloro-2-deoxy-D-glucose

CAS: 14685-79-1

2-Chloro-2-deoxy-D-glucose

Color and Shape: Solid

Molecular weight: 198.60g/mol

Ref: 54-BIC6205

2-Chloro-2-deoxy-D-glucose

CAS: 14685-79-1

Formula: C₆H₁₁ClO₅

Purity: ≥ 98.0%

Color and Shape: White to off-white powder or solid

Molecular weight: 198.60

Ref: 7W-GC4750

Fludeoxyglucose Related Compound B

CAS: 14685-79-1

Formula: C₆H₁₁ClO₅

Molecular weight: 198.60

Ref: 4Z-F-147002

2-Deoxy-2-chloro-D-glucose

Controlled Product

CAS: 14685-79-1

Applications 2-Deoxy-2-chloro-D-glucose is a D-Glucose (G595000) derivative used in the synthesis of sugar nucleotides and oligosaccharides.
References Herr, D., et al.: Euro. J. App. Microbiol., 1, 41 (1975);

Formula: C₆H₁₁ClO₅

Color and Shape: Neat

Molecular weight: 198.60

Ref: TR-D232570

2-Chloro-2-deoxy-D-glucose

CAS: 14685-79-1

2-Chloro-2-deoxy-D-glucose (2CDG) is a chemical compound that has been shown to be an effective inhibitor of hypoxic tumor growth. 2CDG inhibits the production of fatty acids, which are required for cell proliferation and survival. It also has inhibitory properties on the chromatographic system and can be used as a detector in electrochemical methods. The detection of 2CDG in blood serum is used as a diagnostic tool for cancer, with a sensitivity and specificity of up to 100%. This compound has shown promising results for the treatment of hypertension and diabetes.

Formula: C₆H₁₁ClO₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 198.6 g/mol

Ref: 3D-MC06622