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CAS 14691-88-4

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4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl

Description:
4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl, commonly referred to as TEMPOL, is a stable nitroxide radical characterized by its unique structure that includes a piperidine ring with four methyl groups and an amino group. This compound is notable for its paramagnetic properties due to the presence of an unpaired electron, which contributes to its stability and reactivity. TEMPOL is often utilized in various applications, including as a spin label in electron paramagnetic resonance (EPR) spectroscopy, as well as in biological and pharmaceutical research due to its antioxidant properties. It can scavenge free radicals, making it a subject of interest in studies related to oxidative stress and cellular protection. Additionally, TEMPOL has been investigated for its potential therapeutic effects in various conditions, including cardiovascular diseases and neuroprotection. Its solubility in polar solvents and relatively low toxicity further enhance its utility in research and potential clinical applications.
Formula:C9H19N2O
InChI:InChI=1S/C9H19N2O/c1-8(2)5-7(10)6-9(3,4)11(8)12/h7H,5-6,10H2,1-4H3
InChI key:InChIKey=XUXUHDYTLNCYQQ-UHFFFAOYSA-N
SMILES:[O]N1C(C)(C)CC(N)CC1(C)C
Synonyms:
  • (2,2,6,6-Tetramethyl-1-oxy-4-piperidinyl)amine
  • 1-Piperidinyloxy, 4-amino-2,2,6,6-tetramethyl-
  • 2,2,6,6-Tetramethyl-1-oxy-4-aminopiperidine
  • 2,2,6,6-Tetramethyl-4-amino-1-piperidinyloxy
  • 2,2,6,6-Tetramethyl-4-aminopiperidine N-oxide
  • 2,2,6,6-Tetramethyl-4-aminopiperidine-1-oxyl
  • 4-Amino-1-oxyl-2,2,6,6-tetramethylpiperidine
  • 4-Amino-2,2,6,6-tetramethyl-1-piperidinyloxy
  • 4-Amino-2,2,6,6-tetramethyl-1-piperidinyloxyl
  • 4-Amino-2,2,6,6-tetramethylpiperidin-1-oxyl
  • See more synonyms
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