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CAS 146998-27-8

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N(Alpha)-Fmoc-N(Epsilon)-Dabcyl-L-Lysine

Description:
N(Alpha)-Fmoc-N(Epsilon)-Dabcyl-L-Lysine, with the CAS number 146998-27-8, is a synthetic amino acid derivative commonly used in peptide synthesis and bioconjugation applications. This compound features a phenylmethoxycarbonyl (Fmoc) protecting group at the alpha-amino group, which facilitates selective deprotection during peptide synthesis. The epsilon-amino group is modified with a Dabcyl moiety, a fluorescent dye that serves as a quencher in fluorescence resonance energy transfer (FRET) experiments. The presence of these functional groups allows for the incorporation of both protective and reactive functionalities, making it valuable in the design of peptide-based probes and sensors. The compound is typically soluble in organic solvents and exhibits stability under standard laboratory conditions. Its unique structure enables researchers to study protein interactions and dynamics, as well as to develop novel therapeutic agents. Overall, N(Alpha)-Fmoc-N(Epsilon)-Dabcyl-L-Lysine is an important tool in the fields of biochemistry and molecular biology.
Formula:C36H37N5O5
Synonyms:
  • Nα-Fmoc-Nε-Dabcyl-L-Lysine
  • Fmoc-Lys(Dabcyl)-OH
  • Nε-4-[4-(Dimethylamino)phenylazo)benzoyl]-Nα-Fmoc-L-lysine
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