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CAS 147009-08-3

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Frova

Description:
Frova, with the CAS number 147009-08-3, is the brand name for the active pharmaceutical ingredient frovatriptan, which is primarily used in the treatment of migraine headaches. Frovatriptan belongs to the triptan class of medications, which are specifically designed to alleviate migraine symptoms by acting as agonists at serotonin receptors, particularly the 5-HT_1B and 5-HT_1D subtypes. This action leads to vasoconstriction of cranial blood vessels and inhibition of pro-inflammatory neuropeptide release. Frovatriptan is characterized by its relatively long half-life compared to other triptans, allowing for sustained relief from migraine symptoms. It is typically administered orally and is known for its favorable side effect profile, which includes less frequent occurrences of rebound headaches. Common side effects may include dizziness, fatigue, and nausea. As with all medications, it is essential for patients to consult healthcare professionals for appropriate usage and to discuss any potential contraindications or interactions with other medications.
Formula:C18H25N3O6
InChI:InChI=1/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2
SMILES:CNC1CCc2c(C1)c1cc(ccc1[nH]2)C(=N)O.C(CC(=O)O)C(=O)O.O
Synonyms:
  • (3R)-2,3,4,9-Tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide Butanedioic Acid Monohydrate
  • Frovatriptan Succinate Monohydrate
  • Frovelan
  • Migard
  • (3R)-3-(methylamino)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide
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