CAS 147059-72-1: TROVAFLOXACIN

Description: Trovafloxacin is a synthetic fluoroquinolone antibiotic that exhibits broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections, particularly those caused by Gram-positive and Gram-negative organisms. The compound works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription, thereby preventing bacterial cell division and growth. Trovafloxacin is characterized by its relatively high potency against certain pathogens, including those resistant to other antibiotics. It is typically administered orally or intravenously and has a favorable pharmacokinetic profile, allowing for once-daily dosing in many cases. However, its use has been limited due to concerns about hepatotoxicity and the potential for serious side effects, leading to its withdrawal from the market in some regions. Additionally, like other fluoroquinolones, it may be associated with risks of tendon rupture and central nervous system effects. Overall, while Trovafloxacin demonstrates effective antibacterial properties, its safety profile necessitates careful consideration in clinical use.

Formula: C₂₀H₁₅F₃N₄O₃

InChI: InChI=1/C20H15F3N4O3/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24/h1-4,7,10-11,16H,5-6,24H2,(H,29,30)/t10-,11+,16+

InChI key: InChIKey=WVPSKSLAZQPAKQ-CDMJZVDBNA-N

SMILES: O=C(O)C1=CN(C2=NC(=C(F)C=C2C1=O)N3CC4C(N)C4C3)C5=CC=C(F)C=C5F

Synonyms:

• (1α,5α,6α)-7-(6-Amino-3-azabi-cyclo[3.1.0]hex-3-y1)-1-(2,4-difluomphenyl)-6-fluom-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
• 1,8-Naphthyridine-3-carboxylic acid, 7-(1.alpha.,5.alpha.,6.alpha.)-6-amino-3-azabicyclo3.1.0hex-3-yl-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-
• 1,8-Naphthyridine-3-carboxylic acid, 7-[(1α,5α,6α)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-
• 3-Azabicyclo[3.1.0]hexane, 1,8-naphthyridine-3-carboxylic acid deriv.
• 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
• 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
• Cp-99219
• Trovan：CP-99219-27
• Turvel

1,8-Naphthyridine-3-carboxylic acid, 7-[(1α,5α,6α)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-

CAS: 147059-72-1

• Formula: C₂₀H₁₅F₃N₄O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 416.3533095999999

Trovafloxacin

CAS: 147059-72-1

• Formula: C₂₀H₁₅F₃N₄O₃
• Molecular weight: 416.35

Trovafloxacin

CAS: 147059-72-1

Trovafloxacin, a broad-spectrum quinolone antibiotic, exhibits potent activity against Gram-positive bacteria.

• Formula: C₂₀H₁₅F₃N₄O₃
• Purity: 99.27%
• Color and Shape: Solid
• Molecular weight: 416.35

Trovafloxacin

CAS: 147059-72-1

Applications Trovafloxacin is a fluroquinolone antibiotic, recently identified as an inhibitor of pannexin-1 (Panx1) channels. …

• Formula: C₂₀H₁₅F₃N₄O₃
• Color and Shape: Neat
• Molecular weight: 402.37

(1R,5R,6R)-7-(6-Amino-3-Azabicyclo[3.1.0]Hex-3- Yl)-1-(2,4-difluorophenyl)-6-Fluoro-1,4-dihydro-4-Oxo-1,8-naphthyridine-3-carbox

CAS: 147059-72-1

Please enquire for more information about (1R,5R,6R)-7-(6-Amino-3-Azabicyclo[3.1.0]Hex-3- Yl)-1-(2,4-difluorophenyl)-6-Fluoro-1,4-dihydro-4-Oxo-1,8-naphthyridine-3-carbox including the price, delivery time and more …

• Formula: C₂₀H₁₅F₃N₄O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 416.35 g/mol