CAS 147098-20-2

Rosuvastatin Calcium

Description:

Rosuvastatin calcium is a synthetic lipid-lowering agent belonging to the statin class, primarily used to manage hyperlipidemia and reduce the risk of cardiovascular disease. It functions by inhibiting HMG-CoA reductase, an enzyme crucial for cholesterol biosynthesis in the liver, thereby lowering levels of low-density lipoprotein (LDL) cholesterol and triglycerides while increasing high-density lipoprotein (HDL) cholesterol. The substance appears as a white to off-white powder and is soluble in water, which facilitates its absorption in the gastrointestinal tract. Rosuvastatin calcium has a relatively long half-life, allowing for once-daily dosing. It is generally well-tolerated, but potential side effects may include muscle pain, liver enzyme elevations, and gastrointestinal disturbances. The compound is often prescribed in conjunction with lifestyle modifications, such as diet and exercise, to enhance its efficacy in cholesterol management. As with any medication, monitoring for adverse effects and interactions with other drugs is essential during treatment.

Formula: C₄₄H₅₄CaF₂N₆O₁₂S₂

InChI: InChI=1S/C22H28FN3O6S.Ca/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/b10-9+;/t16-,17-;/m1./s1

InChI key: InChIKey=AVDMILNVMOXCHF-DHMAKVBVSA-N

SMILES: C(=C/[C@H](C[C@H](CC(O)=O)O)O)\C=1C(=NC(N(S(C)(=O)=O)C)=NC1C(C)C)C2=CC=C(F)C=C2.[Ca]

Synonyms:

• (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
• (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[N-methyl(n-methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-Heptenoic calcium
• (6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
• (E)-6-[4-(4-fluorophenyl)-6-isopropyl-2-(methyl-methylsulfonyl-amino)pyrimidin-5-yl]-2,4-dihydroxy-hex-5-enoate
• 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)-
• 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), [S-[R*,S*-(E)]]-
• AZD 4522 calcium
• AZD4522 calcium
• Calcium(-1) Anion
• Crestomed
• Crestor
• Fortius
• Razel-F 10
• Rostar
• Rosuvastatin calcium salt
• Rosuvastatin hemicalcium
• Rozavel
• S 4522
• Suvikan

Rosuvastatin Calcium

CAS: 147098-20-2, 287714-41-4

Formula: C₄₄H₅₄CaF₂N₆O₁₂S₂

Purity: >95.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 1,001.14

Ref: 3B-R0180

ROSUVASTATIN FOR SYSTEM SUITABILITY CRS

CAS: 147098-20-2

ROSUVASTATIN FOR SYSTEM SUITABILITY CRS

Formula: C₂₂H₂₈FN₃O₆S

Color and Shape: White. Whitish. Powder., White. Whitish. Powder.

Molecular weight: 481.5376

Ref: 41-Y0001721

ROSUVASTATIN CALCIUM CRS

CAS: 147098-20-2

ROSUVASTATIN CALCIUM CRS

Ref: 41-Y0001719

Rosuvastatin Calcium

CAS: 147098-20-2

Sulfonamides used as drugs

Formula: Ca(C₂₂H₂₇FN₃O₆S)₂

Color and Shape: White Powder

Molecular weight: 1000.28351

Ref: 45-1606015

Rosuvastatin calcium

CAS: 147098-20-2

Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic

Formula: (C₂₂H₂₇FN₃O₆S)Ca

Purity: 98.21% - 99.68%

Color and Shape: White To Off-White Crystalline Solid

Molecular weight: 1001.14

Ref: TM-T1510

6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)-

CAS: 147098-20-2

Formula: C₄₄H₅₄CaF₂N₆O₁₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1001.1374

Ref: IN-DA001EL3

Rosuvastatin calcium

CAS: 147098-20-2

Rosuvastatin calcium

Purity: ≥98%

Molecular weight: 1001.14g/mol

Ref: 54-BUP13993

Rosuvastatin Calcium

CAS: 147098-20-2

Rosuvastatin Calcium

Purity: 97%

Molecular weight: 1001.14g/mol

Ref: 54-IN11947

Rosuvastatin calcium salt

CAS: 147098-20-2

Formula: C₂₂H₂₇FN₃O₆S·5Ca

Purity: 98.0 - 102.0 % (anhydrous basis)

Color and Shape: White, off-white beige-yellow powder

Molecular weight: 500.57

Ref: 7W-GP1717

Rosuvastatin Calcium Salt

CAS: 147098-20-2

Formula: C₂₂H₂₇FN₃O₆S·5Ca

Color and Shape: White To Off-White Solid

Molecular weight: 480.53 0.5*40.08

Ref: 4Z-R-094

Rosuvastatin Calcium

Controlled Product

CAS: 147098-20-2

Formula: C₂₂H₂₇FN₃O₆S·Ca

Color and Shape: Neat

Molecular weight: 1001.14

Ref: 86-MM0936.00

Rosuvastatin Calcium RS

CAS: 147098-20-2

Color and Shape: White Solid Powder

Ref: 2K-1188600021

Rosuvastatin Calcium Salt

Controlled Product

CAS: 147098-20-2

Formula: C₂₂H₂₇FN₃O₆S·Ca

Color and Shape: White To Off-White

Molecular weight: 1001.14

Ref: TR-R700500

Rosuvastatin calcium - Bio-X ™

CAS: 147098-20-2

Rosuvastatin is a drug that belongs to the group of statins. It is used for the treatment of high cholesterol and as an adjunct therapy for patients with coronary heart disease. Rosuvastatin reduces serum cholesterol by inhibiting HMG-CoA reductase, which is the rate-limiting enzyme in the production of cholesterol. Furthermore, this drug has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.

Formula: C₂₂H₂₇FN₃O₆SCa

Purity: (%) Min. 95%

Color and Shape: Powder

Molecular weight: 500.57 g/mol

Ref: 3D-BR164378

Rosuvastatin calcium

CAS: 147098-20-2

HMG-CoA reductase inhibitor

Formula: (C₂₂H₂₇FN₃O₆S)₂Ca

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 1,001.14 g/mol

Ref: 3D-FR27760