CAS 147126-75-8

(2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (FCME)

Description:

(2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (FCME) is a synthetic compound characterized by its unique structural features, which include a fluorinated cytosine moiety and an oxathiolane ring. The presence of the fluorine atom enhances its biological activity, making it a subject of interest in medicinal chemistry, particularly in antiviral and anticancer research. The oxathiolane structure contributes to its stability and potential as a nucleoside analog. FCME is typically studied for its interactions with nucleic acid synthesis and its ability to inhibit viral replication. The menthyl ester group may influence its solubility and permeability, affecting its pharmacokinetic properties. As a chemical entity, FCME is characterized by its specific stereochemistry, which is crucial for its biological function. Its CAS number, 147126-75-8, allows for precise identification in chemical databases and literature. Overall, FCME represents a class of compounds that combine structural complexity with potential therapeutic applications.

Formula: C₁₈H₂₆FN₃O₄S

InChI: InChI=1/C18H26FN3O4S/c1-9(2)11-5-4-10(3)6-13(11)25-16(23)17-26-14(8-27-17)22-7-12(19)15(20)21-18(22)24/h7,9-11,13-14,17H,4-6,8H2,1-3H3,(H2,20,21,24)

SMILES: CC(C)C1CCC(C)CC1OC(=O)C1OC(CS1)n1cc(c(=N)nc1O)F

Synonyms:

• 5-(4-Amino-5-Fluoro-2-Oxo-1(2H)-Pyrimidinyl)-1,3-Oxathiolane-2-Carboxylic Acid 5-Methyl-2-(1-Methylethyl)Cyclohexyl Ester
• [1R-[1(2S*,5R*),2Beta,5Alpha]]-5-(4-Amino-5-Fluoro-2-Oxo-1(2H)-Pyrimidinyl)-1,3-Oxathiolane-2-Carboxylic Acid 5-Methyl-2-(1-Methylethyl)Cyclohexyl Ester
• Fcme
• (2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid menthyl ester
• (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-2H-pyrimidin-1-yl)-[1,3]oxathiolane-2-carboxylic Acid,(2S)-Isopropyl-(5R)-methyl-(1R)-cyclohexyl Ester
• (2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid methyl ester

1,3-Oxathiolane-2-carboxylic acid, 5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2S,5R)-

CAS: 147126-75-8

Formula: C₁₈H₂₆FN₃O₄S

Purity: %

Color and Shape: Solid

Molecular weight: 399.4801

Ref: IN-DA001EMK

(2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate

CAS: 147126-75-8

(2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate

Purity: 95%

Molecular weight: 399.49g/mol

Ref: 54-PC1005995

Emtricitabine Impurity 38

CAS: 147126-75-8

Formula: C₁₈H₂₆FN₃O₄S

Molecular weight: 399.48

Ref: 4Z-E-5859

1,3-Oxathiolane-2-carboxylic acid, 5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2S,5R)-

CAS: 147126-75-8

Purity: 95+%

Molecular weight: 399.480011

Ref: 10-F865652

Emtricitabine Menthyl Ester

Controlled Product

CAS: 147126-75-8

Formula: C₁₈H₂₆FN₃O₄S

Color and Shape: Neat

Molecular weight: 399.48

Ref: TR-E525310

5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester

CAS: 147126-75-8

5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methylcyclohexyl ester is a novel nucleoside analog with antiviral and anticancer properties. It is an inhibitor of influenza virus replication. The compound is also active against human DNA polymerase beta, herpes simplex virus type 1 and 2, and Epstein Barr virus. This compound is synthesized as a phosphate derivative for use in phosphoramidite chemistry for the synthesis of DNA or RNA.

Formula: C₁₈H₂₆FN₃O₄S

Purity: Min. 95%

Molecular weight: 399.48 g/mol

Ref: 3D-NA32529

Emtricitabine Impurity 15

CAS: 147126-75-8

Formula: C₁₈H₂₆FN₃O₄S

Molecular weight: 399.48

Ref: ST-EA-CP-E5052