CAS 147128-77-6

(4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide

Description:

The chemical substance known as (4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide, with the CAS number 147128-77-6, is a heterocyclic compound featuring a thieno-thiopyran structure. This compound is characterized by its unique bicyclic framework, which includes a sulfur atom in the thiophene ring and a hydroxyl group (-OH) at the 4-position, contributing to its reactivity and potential biological activity. The presence of the 7,7-dioxide functional group indicates that it has two sulfonyl groups, which can enhance its chemical stability and solubility in various solvents. The stereochemistry denoted by (4S,6S) suggests specific spatial arrangements of atoms that can influence the compound's interactions and properties. This compound may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry. Its structural features suggest potential applications in drug development, particularly in areas targeting specific biological pathways. However, detailed studies would be necessary to fully understand its behavior and efficacy in biological systems.

Formula: C₈H₁₀O₃S₂

InChI: InChI=1S/C8H10O3S2/c1-5-4-7(9)6-2-3-12-8(6)13(5,10)11/h2-3,5,7,9H,4H2,1H3/t5-,7+/m0/s1

InChI key: InChIKey=NFUQUGUUAUVBMO-CAHLUQPWSA-N

SMILES: O=S1(=O)C2=C([C@H](O)C[C@@H]1C)C=CS2

Synonyms:

• (4R,6S)-5,6-Dihydro-4-hydroxy-6-methylthieno[2,3-b]thiopyran-7,7-dioxide
• (4R,6S)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol,7,7-dioxide
• (4R,6S)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol 7,7-dioxide
• 4H-Thieno[2,3-b]thiopyran-4-ol, 5,6-dihydro-6-methyl-, 7,7-dioxide, (4R,6S)-
• 4H-Thieno[2,3-b]thiopyran-4-ol, 5,6-dihydro-6-methyl-, 7,7-dioxide, (4R-cis)-
• 4h-thieno[2,3-b]thiopyran-4-ol, 5,6-dihydro-6-methyl-, 7,7-dioxide,(4S,6S)
• Dorzolamide hydrochloride seventh step
• Dorzolamide intermediate

4H-Thieno[2,3-b]thiopyran-4-ol, 5,6-dihydro-6-methyl-, 7,7-dioxide, (4R,6S)-

CAS: 147128-77-6

Formula: C₈H₁₀O₃S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 218.2932

Ref: IN-DA001EMH

(4R,6S)-6-Methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol

CAS: 147128-77-6

(4R,6S)-6-Methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol

Purity: 98%

Molecular weight: 218.29g/mol

Ref: 54-OR350339

Dorzolamide Impurity 17

CAS: 147128-77-6

Formula: C₈H₁₀O₃S₂

Molecular weight: 218.29

Ref: 4Z-D-6425

(4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide

Controlled Product

CAS: 147128-77-6

Applications (4R,6S)-4H-Thieno[2,3-b]thiopyran-4-ol, 5,6-dihydro-6-methyl-,7,7-dioxide is an analog of topically-active carbonic anhydrase inhibitor MK-507 also commonly known as Dorzolamide (D535100).
References Blacklock, T., et al.: J. Org. Chem., 58, 1672 (1993); Tempkin, O., et al.: Tetrahedron: Asym., 7, 2721 (1996)

Formula: C₈H₁₀O₃S₂

Color and Shape: Neat

Molecular weight: 218.29

Ref: TR-T344510

Dorzolamide Impurity 10

CAS: 147128-77-6

Formula: C₈H₁₀O₃S₂

Molecular weight: 218.3

Ref: ST-EA-CP-D25017